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E Guardiola

Publications and source records attributed to E Guardiola.

28 records · Page 2Linked to original sources

[An analysis of Spanish biomedical journals by the impact factor].

BACKGROUND: One of the most frequently used parameters for evaluating scientific publications is that of impact factor (IF) published in the Science Citation Index-Journal Citation Reports (SCI-JCR) which evaluates the number of citations a journal receives on behalf of other journals. The present study analyzed the Spanish biomedical journals included in the SCI-JCR by the IF. METHODS: The IF were obtained from the SCI-JCR (1980-89). The journals were evaluated by the IF and the weighted impact factor (WIF) calculated according to WIF = (IF/MIF) x 100 in which MIF = maximum IF of the considered area. RESULTS: Nine Spanish biomedical journals were included in the SCI-JCR, four being basic sciences (Histology and Histopathology, Inmunología, Methods and Findings in Experimental and Clinical Pharmacology, Revista Española de Fisiología) and five clinical journals (Allergologia et Immunopathologia, Medicina Clínica, Nefrología, Revista Española de las Enfermedades del Aparato Digestivo, Revista Clínica Española). Their IF were much lower than the most important journals in each area with the mean (+/- standard deviation) being 0.21 +/- 0.22 (range 0.016-0.627). The mean WIF was 2.88 +/- 4.07 (0.16-12.82). The journals of basic sciences had higher IF and WIF than the clinical journals (p less than 0.05). Only the four journals of basic sciences were included in the SCI. Four journals, those of basic sciences, are preferentially or exclusively published in English and other five are published in Spanish. The differences in IF among these groups were not significant (p = 0.06) while those of WIF were significant (p less than 0.05). The number of Spanish biomedical journals in the SCI-JCR has risen from 1 in 1980 to 9 in 1989 with IF which have evolved variably. CONCLUSIONS: In mind of impact factor, the contribution of Spanish journals is low, with that of biomedical sciences being higher than that of clinical journals. Language and inclusion in the Science Citation Index may explain, at least in part, the low impact factors obtained.

Abstracting and Indexing↗

[Effect of acarbose on glycemia and pancreatic hormone secretion induced by usual meals in Spain].

Acarbose is a pseudotetrasaccharide of bacterial origin which, in a competitive and reversible way, inhibits intestinal alphaglycosidase. Following such mechanism of action, carbohydrates are not split to monosaccharides and, therefore, cannot be absorbed as easily as in normal conditions. Controlled clinical trials have shown the therapeutic usefulness of Acarbose in the treatment of mon-insulin dependent as well as insulin dependent Diabetes, specially in reducing postprandial hyperglycemia and glycosylated hemoglobin levels. The objective of this study was to evaluate the effect of Acarbose when it is used in a diet with a time-schedule and calorie distribution typical of a Spanish environment. A cross-over simple-blind study design was followed, in which 8 healthy volunteers, with ages between 23 and 29 years, took at 8:30 a.m. a 530 Kcal breakfast (18% of the daily total), at 13:30 p.m. a 1.400 Kcal lunch (40%), and at 21:00 p.m. a 1.070 Kcal dinner (36%). Before each of the meals 100 mg of Acarbose (or placebo, following a randomized distribution) were administered, and blood samples were drawn-10, 0, 30, 60, 90, 120, 150 and 180 minutes, in which glucose levels, insulin, pancreatic polypeptide and glucagon were determined. When Acarbose was administered statistically significant differences in glycemia and insulin postprandial figures were observed. It is concluded that when Acarbose is administered at a 100 mg dose (t.i.d.) together with a diet with a typically spanish calorie distribution and time-schedule, it produces a significant lowering in the postprandial glucose and insulin raises.(ABSTRACT TRUNCATED AT 250 WORDS)

Acarbose↗

[International diffusion of the Spanish research on pain. Analysis of the period 1981-1990].

BACKGROUND: The significance of pain in medical practice has excited considerable interest among both practicing physicians and researchers. In Spain, interest in this field has come late. OBJECTIVE: To analyze the international dissemination of Spanish pain research during the period from 1981 through 1990. METHODS: All articles reporting research carried out in Spain and published during the period under study were collected and analyzed if they included the term "pain" as a keyword. The data bases used for collection were CD-ROM versions of Excerpta Medica CD Drugs & Pharmacology and MEDLINE: RESULTS: Articles considering pain to be a main topic numbered 228. Spanish contributions to the field tripled in the period studied. Half the articles were generated by either Anesthesia and Intensive Care or Pharmacology departments and were published mainly in REVISTA ESPANOLA DE ANESTESIOLOGIA Y REANIMACION (51), Medicina Clínica (17) and Revista Clínica Española (10). Most of the published articles reported clinical research (192), particularly in the areas of cancer pain (29), trials (20), and postoperative (20), neurological (15) and joint (12) pain. Most (67.6%) were published in Spanish. Although most articles listed four or more authors, only 2.4% of the authors and 17.7% of the centers published more than three articles. Most studies were carried out in hospitals (69.1%) or universities (18.2%), principally in Catalonia (26.7%), Madrid (18.2%) and Andalusia (17%). CONCLUSIONS: In spite of increased research seen in recent years, the dissemination of Spanish science may be limited because of its publications mainly in Spanish. Research is scattered, with only a small number of authors following a continuous line of research.

Databases, Bibliographic↗