Biomedical subjects
Publications and source records attributed to E Gutschmidt.
An immediate type I allergy elicited by IgE antibodies against pollen of grasses and cereals was demonstrated as the rare cause of palatinal stomatopyrosis (burning palate). The casual relationship was suggested through history and proven by skin, radioallergosorbent and exposition tests.
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14 patients suffering from longstanding alopecia areata totalis or fere totalis were treated with dinitrochlorobenzene (DNCB) over a period of 2 to 11 months. Hair growth was induced in 9 patients. Side effects were not observed so far.
A constant gradual malignant degeneration of verrucous hyperkeratoses was observed in a now 16-year-old poikiloderma congenitale patient although topical immunotherapy of the warty lesions was partially successful and led to an improvement of T-cell functions.
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A new kind of clinical rehabilitation therapy of chronic eczematous patients is reported. It consists of a standardized, work-like activity of the hands increasing in time and intensity. This ergotherapy is coordinated with the clinical treatment. Until now our experiences have shown that the clinical healing as well as the functional reconstruction of the horny layer (alkali resistance, permeability) are not delayed by the work-like skin stress. The instruction and guidance concerning cleaning and skin protective measures are of particular importance. The observation of the course of 77 subjects suggests a positive influence on patients suffering from degenerative eczema whereas the results in patients with multiple allergies do not confirm previous expectations.
Two cases of generalized syringomata showing an uncommon dissemination and density of tumors particularly on thighs, back and abdomen, are demonstrated. Clinically there is similarity with urticaria pigmentosa adultorum. Histological investigation is essential for clinical diagnosis.
The case of a disseminated superficial actinic porokeratosis in a 55-year-old woman is reported which has developed since 10 years. Local application of vitamin-A-acid (retinoic acid) did not improve the dermatoses. The differential diagnosis and some therapeutical consequences (light protecting therapy) are shortly discussed.
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The case of a diffuse plane normolipaemic xanthomatosis in a 74-year-old woman is reported which has developed since about 5 years. There was no sign of any disease of the reticulhistiocytic system. With regard to the prognosis the arterial hypertension is of particular interest.
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Explore the source record for details and available documents.