Studies on the repetitive sequence transcripts of Xenopus oocytes.
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Biomedical subjects
Publications and source records attributed to E H Davidson.
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Many diverse RNA's are synthesized in the lampbrush stage oöcyte of Xenopus, as shown by the presence of different nucleotide sequences in the RNA population. This fact has been established by hybridizing lampbrush stage oöcyte RNA with an isolated nonrepetitive fraction of Xenopus DNA.
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Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge from lipopolysaccharide with significant elevations in profilin transcripts per coelomyocyte.