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Biomedical subjects

E H Norby

Publications and source records attributed to E H Norby.

3 recordsLinked to original sources

Nasal radioiodine activity: a prospective study of frequency, intensity, and pattern.

The nose has been reported as a site of radioiodine accumulation on 131I whole-body scintigraphy. To determine the frequency, intensity, and pattern of nasal radioiodine accumulation, a prospective study was performed on 21 patients referred for 131I whole-body scintigraphy during a 26-mo interval. All patients were dosed with 5 mCi (18.5 MBq) of 131I p.o., and imaged 72 hr later. Ninety-five percent (20/21) of patients had nasal radioactivity greater than background, and in 75% (15/20) of positive patients the pattern of activity was round. Clinical follow-up of these patients has shown no evidence of tumor involvement in the nasal area. We conclude that nasal radioiodine activity is a normal finding. Radioiodine uptake in the nasal area, without clinical suspicion of metastatic disease, should not be considered a criterion for surgical intervention or radioiodine therapy.

Adult↗

PET in clinical practice.

Positron emission tomography (PET) is a nuclear medicine imaging tool that has expanded from its vital role in basic research into clinical medicine. This noninvasive diagnostic modality is used in cardiac perfusion and viability; in neurologic conditions such as epilepsy, dementia, and tumor; and in a wide range of common cancers to diagnose, stage, and monitor therapy. The importance of PET in clinical practice is growing rapidly, and the number of PET centers across the country is increasing. It is imperative, therefore, that physicians are familiar with PET, and know where this tool can be the most useful and cost-effective modality for patient management.

Cost-Benefit Analysis↗

Case studies in PET.

In recent years primary care providers have been increasingly called on to broaden their management of patients, particularly in their role as gatekeepers to reduce healthcare costs. Obviously a wide spectrum of specialty involvement exists, ranging from the classic family practitioner managing all of the common diseases and referring challenging cases to specialists, to the internist with a background and interest geared toward handling more specialized neurologic, cardiac, or oncologic diseases. Whatever the case, primary care providers can have a great impact on diagnosis and management of illness by consulting with the radiologist about the use of the emerging technology of positron emission tomography (PET).

Adult↗