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Biomedical subjects

E H Rang

Publications and source records attributed to E H Rang.

7 recordsLinked to original sources
PubMed1988

Problems of cervical cancer screening programmes.

The feasibility of using an age-sex register as a basis for a cervical cancer screening programme was investigated in a London practice serving both inner city and suburban populations. Only about 25% of 810 women aged 35-59 years who had not recently been screened responded to an invitation to attend a practice well woman clinic for a cervical smear. Nearly 30% of the invitations were returned ;not known at this address' and there was no reply from the remaining 45%. A high proportion of incorrect addresses considerably reduces the effectiveness of a cancer screening programme based on an age-sex register covering an area with a mobile population and also makes it difficult to follow up women with abnormal smears adequately. Opportunistic screening remains essential and every effort should be made to encourage women to be responsible for their own cancer screening programmes.

Adult↗
PubMed1983

A study of cancer of the breast and other sites in women after total colectomy and ileostomy for non-malignant disorders.

To assess the role in breast-cancer aetiology of oestrogenic substances apparently produced by intestinal bacteria from faecal residues associated with a high-fat diet and other absorbable and possibly carcinogenic colonic substances, cancer incidence and mortality were studied in 2425 women in the UK who had previously had total colectomy and terminal ileostomy, mostly for ulcerative colitis for Crohn's disease. The incidence of breast cancer in this group of women was no lower than would be expected, although there was a slight deficiency of deaths from this cause. These findings suggest that, at least in adult life, the colon is not involved in the aetiology of breast cancer. There were pronounced excesses of rectal and bile-duct cancers in ulcerative colitis patients despite previous colectomy.

Adult↗
PubMed1981

Cancer in furniture workers.

A follow-up study of 5371 men who had worked in 1 or more of 9 furniture factories in Buckinghamshire for an average of 19 years up to 1968 is reported. The incidence of nasal adenocarcinoma in furniture workers taken as a whole was found to be about one hundred times that expected in the local population, and a significant relationship was found between increasing incidence of the tumour and increasing dustiness of work within the cohort. Similar comparisons with the local population produced no evidence for an increased risk of cancer of any other site in the furniture workers including bronchial cancer and malignant disease of the reticulo endothelial system. However, when comparisons were made between men exposed to different amounts of dust within the industry the incidence and mortality of bronchial cancer increased with increasing dustiness of work the latter trend but not the former being statistically significant. This trend is not due to differences in smoking habits among the groups of men. No trends of increasing incidence or mortality of other sites of cancer with increasing dustiness of work were found.

Adenocarcinoma↗
PubMed1981

Nasal cancer in England and Wales: an occupational survey.

A national survey of the incidence of nasal cancer in England and Wales during the period 1963-7 with special reference to occupation confirmed the well-known increases in incidence of nasal cancer in cabinet makers and wood machinists, together with the absence of any significant increase in carpenters and joiners, and the increases in boot and shoe operatives and repairers, and in nickel smelters in South Wales. The significant excesses of cases found among coalminers, furnacemen in the gas, coke, and chemical industry, and furnacemen and labourers in foundries may be associated with exposure to coal and coke dust or may be spurious. No excess of nasal cancer was found among male textile workers. Excesses of uncertain significance were found among tailors and dressmakers, bakers and pastry cooks, and printers. Apart from the well-known relationships between adenocarcinoma and work in the furniture and footwear industries there is no definite indication in this survey of any association between a particular histological type of nasal tumour and occupation in England and Wales.

Adolescent↗