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Biomedical subjects

E H Shuford

Publications and source records attributed to E H Shuford.

7 recordsLinked to original sources
PubMed1979

A demographic study of disease due to Mycobacterium kansasii or M intracellulare-avium in Texas.

The number of patients reported th have disease due to Mycobacterium kansasii or M intracellulare-avium has increased in Texas from January 1967 to December 1976, in contrast to a decrease in tuberculosis. Presented is an analysis of 1,409 patients infected with M kansasii and 706 patients infected with M intracellulare-avium. The former group clustered in urban areas with more than twice the incidence compared to nonurban areas (P less than 0.001). The latter group was more diffusely distributed with approximately twice the incidence in nonurban areas compared to urban areas (P less than 0.001). The average age of the group infected with M kansasii was 50 years and of the group infected with M intracellulare-avium 58 years. In patients infected with M kansasii only, the average age was significantly higher for men than women. There was a male predominance in both groups, ie, 3:1 in M kansasii and 2:1 in M intracellulare-avium. Persons with Spanish surnames had a low incidence of disease due to M kansasii. No other racial or ethnic association was noted. The various factors involved in determining the atypical mycobacterial diseases are discussed.

Adolescent↗
PubMed1976

The value of the skin test and complement fixation test in the diagnosis of chronic pulmonary histoplasmosis.

Histoplasmin skin test results in patients with chronic pulmonary histoplasmosis from Missouri and Texas were compared to results in a previous study of U.S. Navy recruits. When consideration was given to geographic areas from which persons from each group were admitted to the study, it was found that the recruits were as likely to have a positive skin test as were those with the disease. In a similar manner, the Texas histoplasmosis patients were compared to groups of patients from that state with chronic obstructive pulmonary disease and with pulmonary tuberculosis. Again, no significant differences were found. It was concluded that the histoplasmin skin test is not of value in the diagnosis of chronic pulmonary histoplasmosis. Histoplasmosis complement fixation test data from the chronic pulmonary histoplasmosis group were compared to data from the chronic obstructive pulmonary disease and pulmonary tuberculosis groups. The usefulness of the complement fixation test in chronic pulmonary histoplasmosis is limited, as with any test, by false-positive and false-negative reactions. A decision theory method was used to define the limits of usefulness.

Chronic Disease↗
PubMedDate not supplied

Ferruginous bodies in sputa of former asbestos workers.

Routine cytopathologic examinations were performed at six-month intervals on sputum specimens from 628 former asbestos workers and 138 control patients. The occurrence of ferruginous bodies in sputa is found to increase as a logarithmic function of the length of occupational exposure to asbestos in workdays. No significant association is found between the occurrence of ferruginous bodies and the worker's age, smoking history, degree of cellular epithelial atypia, or time since last exposure. We conclude that the presence of ferruginous bodies in sputa is evidence of probable significant occupational exposure to asbestos dust. Their absence does not indicate lack of exposure. We can also conclude that routine cytopathology procedures are sufficient for the detection of ferruginous bodies in sputa.

Asbestos↗