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Biomedical subjects

E H Wyatt

Publications and source records attributed to E H Wyatt.

14 recordsLinked to original sources
PubMed1992

Pyoderma gangrenosum: associations revisited.

Fourteen cases of pyoderma gangrenosum were seen over a period of 24 years at the Hull Royal Infirmary Dermatology Department. Several associated conditions were found. Seven cases were associated with rheumatoid arthritis of which five were sero-positive, including one with Felty's syndrome. One case was associated with both ulcerative colitis and psoriasis; one with polycythemia rubra vera; two patients had diverticular disease including one who also had rheumatoid arthritis; one had positive syphilis serology. In three cases there was no significant associated disease identified. Ten out of the fourteen cases were women, indicating a female preponderance by a ratio of about 2F:1M; a figure similar to that stated by Seitzinger. The age of presentation ranged from 30 to 80 years.

Adult↗
PubMed1990

Rosacea and ulcerative colitis: a possible association.

Although rosacea was formerly believed to be associated with gastrointestinal upsets, no one any longer finds a significant association between rosacea and the intestinal tract. We describe four patients with a combination of ulcerative colitis and rosacea. In all four, ulcerative colitis preceded the onset of severe papulopustular rosacea, and we therefore feel that the severity of rosacea could have been due to the associated bowel disorder. In one, the severity and poor initial response of rosacea to treatment was clearly related to the activity of the ulcerative colitis, and the rosacea improved only after proctocolectomy. While it is possible that this purported association is fortuitous, we report these cases in the hope that others may have seen this combination of diseases, to our knowledge previously unreported.

Adult↗
PubMed1989

Skin necrosis in giant cell (temporal) arteritis: report of three cases.

Three elderly, female patients presented with scalp ulceration. One developed sudden blindness before the ulceration of the scalp. Biopsy from the ulcerated area in this patient did not show evidence of giant cell arteritis, but the two other patients had histological evidence of giant cell arteritis and one of these also became blind.

Aged↗
PubMed1988

Genetic control of sebum excretion and acne--a twin study.

Sebum excretion and acne grades were measured in 20 pairs each of identical and non-identical like-sex twins. The identical twins had virtually identical rates of sebum excretion (P greater than 0.05), but they had a significantly different degree of acne severity (P less than 0.01). The non-identical twins had significantly different sebum excretion rates (P less than 0.01) and acne grades (P less than 0.01). These findings suggest that sebum excretion is under genetic control and the development of clinical lesions is modified by environmental factors.

Acne Vulgaris↗
PubMed1988

Pilomatricoma (Malherbe). A clinical and histopathologic survey of 78 cases.

Seventy-eight cases of pilomatricoma are reported. The unexpected findings are new lesions occurring in middle and old age; the lack of association with other diseases; and the large number of lesions located deep in the skin. As contemporary knowledge of the nature of this disorder is advancing, it is suggested that the eponymous title be abandoned.

Adolescent↗
PubMed1977

Scanning electron microscopy of hair. Observations on surface morphology with respect to site, sex and age in man.

The cuticular scale pattern of adult human terminal hair sampled from 10 different body sites was examined by scanning electron microscopy and showed: (1) differences according to site, the size of the cuticular scales being significantly greater in scalp hair than in hair taken from the nine other sites; (2) differences according to sex, the size of cuticular scales of facial, axillary and abdominal hairs being significantly larger in females; and (3) differences according to age, the size of cuticular scales from scalp hairs being significantly smaller in older than younger people.

Adolescent↗
PubMed1975

Lichen planus and ulcerative colitis.

Three patients with ulcerative colitis and lichen planus are reported and similar cases in the literature discussed. Similarities in the pathology of the two conditions are outlined.

Adult↗