[Evaluation of the measurement of serum bilirubin using the Gambino autoanalyzer].
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Biomedical subjects
Publications and source records attributed to E Hamada.
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Cholestatic hepatocellular carcinoma, which grows into the bile duct and causes obstructive jaundice, is rare and difficult to diagnose. A case is presented in which cholestatic hepatocellular carcinoma was detected by deposit of Lipiodol. This is also the first case that was successfully treated by endoscopic retrograde biliary drainage and transcatheter arterial embolization.
BACKGROUND: Active chronic osteomyelitis or complicating osteomyelitis are difficult to be diagnosed by radiological imaging modalities, such as plain radiograph and CT. They frequently cause increased bone remodeling, leading to nonspecific uptake of Tc-99m-bone scan agents and gallium-67. New radiopharmaceuticals with greater infection avidity are being developed, including the nonspecific polyclonal immunoglobulin (IgG) labeled with technetium-99m. Tc-99m-IgG may be available as a ready to use kit, with no reported side effects, low patient absorbed radiation dose and low cost. MATERIAL AND METHODS: 23 bone segments with suspected active chronic osteomyelitis or violated bone osteomyelitis were studied by Tc-99m-IgG scintigraphy. All patients underwent standard three-phase bone scintigraphy using methylene diphosphonate (Tc-99m-MDP), gallium-67 scintigraphy and plain radiographs, compared with clinical evaluation and laboratory tests values. RESULTS: Infection was found in 8 sites. Sensitivity and specificity for Tc-99m-MDP, gallium-67 and Tc-99m-IgG scintigraphy were, respectively, 88 and 36%, 75 and 73%, 88 and 82%. CONCLUSION: Tc-99m-IgG may be usefull in the scintigraphic evaluation of osteomyelitis.
The volume of nasal secretion is so small that it is difficult to measure. We placed a thread on the anterior surface of the inferior turbinate to measure the volume of nasal secretion in normal subjects and patients with nasal allergy. In 24 normal subjects, the average nasal secretion amounted to 1.09 microliter/min. In 48 patients with nasal allergy, the volume of nasal secretion (1.94 microliter/min) decreased significantly after nasal spraying: the subjective symptoms of sneezing, rhinorrhea, nasal obstruction, inconvenience in daily life and the objective signs such as watery rhinorrhea abated. The thread test results showed a good correlation with the above items in a quantitative analysis. The thread test is a simple way to measure a small volume of nasal secretion, and a useful indicator of the severity of watery rhinorrhea in patients with nasal allergy.