Biomedical subjects

E Harms

Publications and source records attributed to E Harms.

147 records · Page 9Linked to original sources

PubMedDate not supplied

[Clinical aspects of premature rupture of the membranes].

In this study all deliveries with premature rupture of the membranes (VBS) between 1978 and the midst of 1981 were compared and statistically analysed using a control collective, which consisted of the sum of the respective following delivery. A premature rupture of the membranes was found in 18.1 per cent. We observed a VBS more often in case of increasing age of the mother and significantly more often for primiparae. An infection of the urinary tract seemed to increase the risk of an VBS. The latent period is longer, if the VBS occurred in the early pregnancy. There was no difference between both groups according to the course of birth, the frequency of KPDA, the pressing period and the period of dilatation. Complications with the umbilical cord could not be found more often in the collective of premature rupture of the membranes than in the control group. The umbilical cord prolapse even was rarer in case of premature rupture of the membranes. Difficulties in adaptation and the respiratory distress syndrome could be found significantly more often in the group of VBS, according to the higher rate of premature children in this collective. The possible stimulating effect of the VBS on the induction of the fetal lung maturity was reserved by the higher rate of neonatal infections in case of longer latent periods. We found the amnion infection syndrome in 2.1 per cent if the latent period was less than 24 hours, 10.7 per cent if it was longer than 48 hours and more than 15 per cent if it was 72 hours and more.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMedDate not supplied

[Experiences with ambulatory delivery].

This study summarizes the experiences with ambulant delivery in the St. Elisabeth Hospital in Cologne between 1979 and October 1982. The ambulant deliveries during this period were compared with a control group of normal vaginal births in the hospital. There were 211 women in each group. Questionnaires were sent to those women who had ambulant births, and the answers formed an important part of this study. Of all the intended ambulant births, 18.5% had to be refused because of possible complications. The results of the study show that the risks during birth for mother and child in both groups, were identical, and any complications arising were wide and various. In our opinion the main risk is the "Icterus neonatorum". The number of peridural anaesthesia was significantly lower in the ambulant delivery group. From the questionnaires we had a clearly positive reaction to ambulant delivery. For the newborn infant there is a decisive risk, so that ambulant delivery should only be used as an alternative in order to avoid home delivery.

Ambulatory Care↗

PubMedDate not supplied

Nephropathic cystinosis (CTNS-LSB): construction of a YAC contig comprising the refined critical region on chromosome 17p13.

A yeast artificial chromosome (YAC) contig was constructed encompassing the entire region on chromosome 17p13 where the autosomal recessive disorder infantile nephropathic cystinosis (MIM 21980, CTNS-LSB) has been genetically mapped. It comprises seven clones ordered by their content of a series of six sequence-tagged sites (STSs). Fluorescence in situ hybridisation (FISH) revealed two chimaeric clones. The order of four polymorphic STSs mapped with the contig was consistent with that of the known genetic map with the exception of markers D17S1583 (AFMb307zg5) and D17S1798 (AFMa202xf5) where a telomeric location of D17S1583 was inferred from the contig; two non-polymorphic STSs were localised within the marker frame-work. From the analysis of recombination events in an unaffected individual as defined by leucocyte cystine levels we support the high-resolution mapping of this region to a small genetic interval and show that it is entirely represented on a single, non-chimaeric YAC clone in the contig.

Chromosome Mapping↗