[Acute epiglottitis in children].
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Biomedical subjects
Publications and source records attributed to E Hartemann.
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Concentrated Totamin was administered by venous infusion in 32 pediatric patients, aged 2 days to 13 years. In 17 cases (group "A"), patients received Totamin by separated and isolated infusion, which was followed by serum glucose and electrolytes infusion. N intake was 0.17-0.32 g/kg/day (m = 0.23), caloric intake was 5-50 cal/kg/day (m = 25), duration of treatment was 5,17 days. In 15 cases (group "B") patients received Totamin, serum glucose and electrolytes simultaneously. N intake was 0.07-0.26 g/kg/day (m = 0.17), caloric intake was 20-72 cal/kg/day (m = 47), duration of treatment was 5 days. The N positive or equilibrate total positive balance ratio is identical in both the groups = 12/17 (70.6%) in group "A" and 10/15 (66.7%) in group "B". But in 11 patients (5 of group "A" and 6 of group "B") which received an identical N intake (0.20 g/kg/day) N balance was negative in 5 (A) and positive in 6 (B). Thus its appears that for an identical N intake, serum glucose infusion simultaneously with concentrated Totamin, is a more efficacious treatment than alternate infusion. Simultaneous infusion produces and better utilisation of Totamin and a N positive balance.
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One the basis of two special typical cases, the authors detail the symptoms and signs and consider the physiopathology of inappropriate secretion of antidiuretic hormone related to vincristine. Urinary ADH was measured in both cases. ADH levels could be studied on ten consecutive occasions during the course of one of the cases (obs. n 1). Eleven similar cases have been found in the literature. ADH was measured in only three of them. Methods of treatment are considered, with particular emphasis on the role of demeclocycline.
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