PubMed Health⌕ Search

Biomedical subjects

E Helmes

Publications and source records attributed to E Helmes.

44 records · Page 3Linked to original sources
PubMed1983

Note on the reliability of three MMPI short forms.

The Mini-Mult, FAM, and MMPI-168 were evaluated for correspondence with the full form MMPIs of 252 adult psychiatric inpatients. Although the correlations of each short form's estimated full-scale score with the corresponding actual full-form scale were high, only the FAM was able to reasonably predict the full-form single high-point code. The range of difference scores between short forms and the corresponding full-form scales was very wide and there was a low agreement rate with the full-form. These results contradict those of Newmark, Ziff, Finch, and Kendall (1978) and raise doubts about the utility of these three short forms.

Female↗
PubMed1983

Inter-rater reliability of twelve diagnostic systems of schizophrenia.

The present and past symptomatology of 31 chronic schizophrenics was rated by four independent judges, two experienced clinical psychiatrists and two psychiatric residents, in a context more representative of actual clinical practice than most research studies. Ratings were made on 64 symptoms derived from 12 diagnostic systems, based on either live or videotaped interviews for present symptomatology and case records for past symptomatology. Inter-rater reliabilities were higher for present than for past symptoms, and in general did not approach those reported for highly trained raters. There were no differences between live and videotaped interviews. Diagnostic systems differed widely in rater agreement. The most consistent across both past and present symptomatology were the systems of Langfeldt, Schneider, and DSM-III, for which the level of reliability was consistent with other studies.

Adult↗
PubMed1982

A comparison of methods of normalizing a discrete distribution.

Normal distributions are the foundation of modern statistical procedures, which differ in their sensitivity to violation of the assumption of normality. This paper reports on the effectiveness of two different methods of normalizing distributions of discrete test score data. The scores of 971 Ontario high school students on the 22 scales of PRF-E (Jackson, 1974) were normalized using two variants of the cumulative proportions method and by a rank method. Neither cumulative procedure appreciably altered the modality or skewness of the distributions. The rank method succeeded in normalizing all the distributions, except for an occasional case of platykurtosis. It was concluded that normalization by ranks is to be preferred over cumulative methods for use in situations in which a statistical procedure is sensitive to violations of normality.

Adolescent↗
PubMed1981

Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease.

A double-blind, placebo-controlled trial of 2-dimethylaminoethanol was undertaken in 27 patients with moderately severe or severe Alzheimer's disease. Of 13 patients in the drug group, 6 were withdrawn in the first 5 weeks of the trial because of side effects, which included drowsiness and retardation, with an increase of confusion and mild elevation of blood pressure. No significant benefit appeared from the drug treatment.

Aged↗
PubMed1980

Validation of the 16 PF in a psychiatric setting.

Used the 16 PF in a group screening battery for psychiatric inpatients. Validation was carried out using psychiatric diagnoses as the criterion. Four hundred and sixty-three patients were grouped into eight traditional diagnostic groups. Discriminant analysis was used to predict group membership and multivariate profile analysis was used to compared group means. No differences in profile elevation or shape were found, and four discriminant functions could classify correctly only 22% of the patients. Results indicated that the 16 PF is unsuitable for discriminating among psychiatric diagnostic groups.

Adult↗
PubMedDate not supplied

Profiles of cognitive decline in Alzheimer disease.

Most recent studies have used only two observations to estimate the rate of cognitive decline in patients with Alzheimer disease (AD); few have data taken from more than a 2-year period; and none report on autopsy-verified cases. Repeated observations over the complete course of the disease are necessary to quantitatively evaluate hypotheses such as the triphasic linear model of Brooks et al. (1993). The goal of this study is to compare the triphasic linear and quadratic models of decline in a group of 12 AD patients confirmed at autopsy with a group of age- and sex-matched normal control subjects. Both groups were taken from the University of Western Ontario Dementia Study, and the Extended Scale for Dementia was used as the outcome measure. The squared multiple correlation as a measure of goodness of fit suggested the superiority of the more parsimonious quadratic model over the triphasic linear model. Quantitative models more accurately reflect the profiles of change in AD and may prove more sensitive in measuring the effects of drugs on these patterns.

Aged↗