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E Heron

Publications and source records attributed to E Heron.

11 recordsLinked to original sources
PubMed2002

[Thyroid orbital pathologies in ophthalmological settings].

OBJECTIVE: To illustrate the originality and diversity of an ophthalmologic pathology associated with a thyroid disease (OATD), we report 42 cases of patients hospitalised or having consulted an ophthalmologic department for this disease over a period of 4 years. METHOD: Each patient was assessed by an endocrinologist and an ophthalmologist. Data included the OATD severity score, date of occurrence compared with the thyroid disease and determination of thyroid function and immune abnormalities. RESULTS: Patients were aged a mean of 48.9 + 15.3 years; 65% were women and 39% smokers. OATD preceded the thyroid disease in 38% of cases, was concomitant in 40% and successive in 21%. Thirty-six percent of cases were mild, 45% moderate and 19% were severe. One patient out of 5 had exhibited a period of iatrogenic hypothyroidia. The majority (81%) presented with Basedow's disease; 14% Hashimoto's disease; 73% anti-TSH receptor antibodies and 56% anti-thyroperoxidase antibodies. Two profiles of patients with OAMT were identified. A first group with severe OATD: Basedow's disease, presence of anti-TSH receptor antibodies and a period of iatrogenic hypothyroidia in half of the cases. A second group in which the occurrence of OATD preceded diagnosis of a thyroid disease: generally non-severe forms with varying thyroid status, strongly related to the moment at which the patient consulted, compared with the progression of the ophthalmologic and thyroid affections. CONCLUSION: When faced with signs evoking OATD, these data emphasize the need for an evaluation of thyroid status and determination of the antibodies implied in Basedow and Hashimoto's disease. After initiation of synthetic anti-thyroid or radioactive iodine therapy, the evolution of the thyroid and ophthalmologic status of hyperthyroid patients must be carefully monitored.

Adult↗
PubMed1999

Intracerebral calcification in systemic sclerosis.

BACKGROUND AND PURPOSE: Advanced cerebrovascular wall calcification was recently observed at autopsy in 2 patients with systemic sclerosis. To further investigate this issue, we conducted a prospective CT study of scleroderma patients to detect intracerebral calcification. METHODS: Thirty-seven consecutive patients with systemic sclerosis underwent unenhanced brain CT. Images were blindly interpreted, together with those of 2 age-matched (+/-1 year) and sex-matched control subjects per patient. RESULTS: Intracerebral calcification was found in 12 patients (32.4%) and 7 controls (9.5%) (P=0.006). Among the patients, intracerebral calcification was associated with the duration of Raynaud's phenomenon (P=0.005) and not with age (P=0.086). CONCLUSIONS: Intracerebral calcification is closely associated with scleroderma, which suggests that scleroderma causes primary cerebrovascular changes.

Adult↗
PubMed1995

Reactive hyperemia unmasks reduced compliance of cutaneous arteries in essential hypertension.

To evaluate changes in distal cutaneous arteries during hypertension, we used a noninvasive method to assess the compliance and vascular resistance of the hand radial arteries, mainly distributed to the skin, in 10 normotensive and 10 hypertensive (HT) men. Radial artery diameter and blood velocity were measured by means of pulsed Doppler concomitantly with measurements of finger arterial pressure by photoplethysmography. Hand radial vascular resistance was calculated as the ratio of mean arterial pressure to mean radial blood flow. A simple resistive-capacitive model of large and small arteries of the hand allowed us to evaluate arterial compliance from the exponential slope of finger diastolic pressure decay and vascular resistance. Measurements were made at baseline and during reactive hyperemia after 5 min of complete occlusion of the brachial artery with a pneumatic cuff. Except for pressure, there were no baseline differences between the groups. In normotensive and HT subjects, hyperemia increased radial artery diameter and blood velocity (P < 0.001) and compliance (P < 0.01 and P < 0.05, respectively) and decreased mean pressure (P < 0.01 and P < 0.001, respectively) and resistance (P < 0.001). During hyperemia, the only difference between the groups, except for pressure, was lower compliance in HT subjects (P < 0.01). Moreover, compliance during hyperemia negatively correlated with baseline mean pressure (P = 0.001). Thus hyperemia unmasked reduced compliance in the HT patients but did not show abnormal resistance, suggesting that the elastic properties of the hand skin radial arteries might be more sensitive than their resistive properties to high blood pressure.

Adult↗
PubMed1994

Thrombotic primary pulmonary hypertension in an HIV+ patient.

We report a case of severe primary pulmonary hypertension occurring in an HIV+ patient in whom lung biopsy and post-mortem examination were consistent with thrombotic pulmonary arteriopathy. To the best of our knowledge, this histological pattern has not been previously reported in HIV+ patients with primary pulmonary hypertension.

Adult↗
PubMed1981

Visual acuity and test performance.

Evaluation of scholastic achievement (American College Testing Service) test scores confirms previous reports that persons with poor visual acuity perform better on these tests than individuals with normal or superior acuity.

Adolescent↗
PubMedDate not supplied

My last shift.

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Acquired Immunodeficiency Syndrome↗