PubMed Health⌕ Search

Biomedical subjects

E Hienzsch

Publications and source records attributed to E Hienzsch.

14 recordsLinked to original sources
PubMed1979

A contribution to the formation mechanism of calcium oxalate urinary calculi. IV. Experimental investigations of the intrarenal crystallisation of calcium oxalate in rabbit.

Rabbits were given glyoxylic acid to induce intrarenal calcium oxalate crystal formation. The point of crystallisation in the renal tubule, the structure and the composition of the intrarenal crystals were studied. The initial crystallisation takes place in the proximal tubule. Calcium phosphate formation was excluded by microprobe examination. The comparison of the structures of the intrarenally formed crystals with those of Whewellite stones by scanning electron microscopy and the examination of isolated crystals by x-ray diffraction showed the intratubular crystals to consist of Whewellite.

Animals↗
PubMed1979

Scanning electron microscope and microprobe investigation of phosphate phases in uroliths.

In uroliths various phosphate phases can be detected which indicate different formation conditions. Structure and topography of the respective phosphate phases are characterized by scanning electron microscopy and microprobe techniques. Trace element enrichment is investigated and illustrated; for example, sulfur is found preferentially in carbonate apatite. From the distribution of the phosphate phases, conclusions can be drawn concerning the urolith genesis.

Crystallography↗
PubMed1977

[Various problems in urinary calculi].

After evaluation of the essential parameters concerning urinary calculi and patient with the help of adequate computer programmes in more than 30,000 persons some conspicious trends could be established. The necessity of operative removal of calculi is still relatively high in the most frequent species of calculi whewellite, weddellite, uric acid, struvite and carbonate apatite. Thus nearly 65% of all struvite and carbonate apatite calculi must be operatively removed in women. For individual species of stones with statistical certainty (alpha=0.01) the preference of the right kidney in women and of the left kidney in men is established. The summer months bring an increased risk of stone formation. The spontaneous passages show a highly significant increase from July to October (alpha=0.01), compared with the winter and spring months.

Carbonates↗
PubMed1977

Mass spectrometric trace element analysis of calcium oxalate uroliths.

Mass spectrometric trace element analysis of whewellite and weddellite uroliths revealed 55 elements, from which 20 could be well assessed quantitatively. The total trace element content in weddellite increased by 77.5% with respect to whewellite, the main portion being made up from Na, P, Mg, and Cl. In physiological conditions weddellite is stabilized by trace elements. The importance of trace element analysis of Si, Al, Sr, Rb, S, F, Cl, and Br in uroliths is indicated.

Calcium↗
PubMed1977

[Effect of ionizing energy on the bladder dilated by dura, with special reference to the implantation technic. Animal experimental study].

On 60 female rabbits we examined the influence of the postoperative irradiation on the urinary bladder dilated by liophilized human dura after resection of the wall. Compared with former examinations as to the implantation technique the submucous deposition of the dura and fixation with single-button U-sutures (chromic catgut 000) has proved as superior. Vascular trophic disturbances on the margins of the resection could not be proved. When 4,500 R, 6,000 R and 7,500 R were irradiated the regeneration process through the dura serving as "live" rail retarded considerably. Problems in connection with the suture technique and the total focal dosage are discussed taking into consideration literature.

Animals↗
PubMed1976

A contribution to the formation mechanism of calcium oxalate urinary calculi. I. Stabilising urinary constituents in the formation of weddellite.

25 to 30% of calcium oxalate urinary calculi consist of the metastable Weddellite crystal phase. By fractionation of urine it was found that mineral substances are stabilising factors. The stability was checked in dry condition at room temperature at 38 degrees C and at 110 degrees C. These results could be confirmed by precipitation from synthetic solutions. Mg, Zn, Ni, Co, Mn and Cu individually, and above all in combination, promote the formation of Weddellite. The formation of mixed crystal phases must be considered one of the main factors for the stabilisation of Weddelite in the urinaty calculus.

Calcium↗
PubMed1976

A contribution to the formation mechanism of calcium oxalate urinary calculi. II. In vitro experiments concerning the theory of the formation of Whewellite and Weddellite urinary calculi.

In vitro investigations of the formation of Whewellite or Weddellite are described. By means of different precipitation models the influence of cationic minerals on the formation of Weddellite could be observed. The possible conversion of Weddellite into Whewellite in vivo is demonstrated by in vitro experiments. A theory of the formation of Weddellite or Whewellite urinary calculi is developed on the basis of the results obtained.

Calcium↗
PubMed1976

Crystaloptical and spectroscopical findings with calcium oxalate crystals in the urine sediment: a contribution to the genesis of oxalate stones.

Transmitted light microscope and scanning electron microscope investigations reveal various shapes of urine calcium oxalate crystals. In addition to tetragonal bipyramids, weddellite forms further crystal shapes that have been heretofore interpreted exclusively as whewellite crystals. Weddellite is stabilized by urine foreign ions. In vivo formation of whewellite crystals occurs with massive crystallization only.

Animals↗
PubMed1975

Uric acid dihydrate as urinary calculus component.

The analysis of uric acid dihydrate was performed using infrared spectroscopy and X-ray diffraction. Both methods permit differentiation with regard to uric acid. Pure uric acid dihydrate was prepared according to a modified technique and the dA values (lattice distances (of A) were determined from several recordings. The extreme instability of the synthetic uric acid dihydrate is stressed, and the conversion speed is determined. During the evaluation of 7,750 analyses of urinary calculi in the course of the past 3 years, 1,126 (14.5 per cent) uric acid calculi and 283 (3.7 per cent) with a mixed portion of uric acid dihydrate were found.

Drug Storage↗
PubMed1975

New aspects in combined treatment of urinary bladder carcinoma.

To further improve the results of treatment of malignant processes of the urinary bladder, the authors reviewed in detail 420 cases under combined treatment. They found the following results: (1) In 96 (38.4%) out of 250 cases, the cystoscopically normal mucosa distant from the tumour showed histologically definite cancer tissue. (2) The destruction of residual tumour elements by ionising energy after operation depends on the relation between tumour and connective tissue. If there is sufficient connective tissue residual tumours may be destroyed in all probability, otherwise prognosis is poor. (3) In case of tumour cell mass formation in the microspace without active connective tissue, a curative effect by means of ionising energy after operation is not to be exptected, whether there is a multilocular development of carcinoma or not. Surgical treatment has to be extended according to the condition.

Carcinoma in Situ↗