PubMed Health⌕ Search

Biomedical subjects

E Housset

Publications and source records attributed to E Housset.

At least 19 recordsLinked to original sources
PubMed1990

[Idiopathic and secondary Raynaud's phenomenon. A comparative psychosomatic approach].

Thirty subjects with Raynaud's phenomenon admitted for determination of its cause underwent psychological examination. Raynaud's phenomenon was regarded as primary in 14 cases, secondary (usually to scleroderma) in 13 cases and eluding classification in 3 cases. The mean age of patients with primary Raynaud's phenomenon was higher than in the other groups. Interviews and psychological tests were carried out with all but 2 patients and all investigators being totally unaware of the aetiological category. Patients with secondary Raynaud's phenomenon significantly differed from those with primary Raynaud's phenomenon in their personality patterns, attitudes towards interlocutors and way of coping with conflicts. Patients with primary Raynaud's phenomenon were characterized by a relatively frequent hysterical personality and by their dodging behaviour when faced with their own aggressiveness. Patients with secondary Raynaud's phenomenon were found to be more distant, more conformist, more able to control their emotions and seemed to be less inclined to seek help when in trouble. Such findings suggest that Raynaud's phenomenon has a "psychosomatic" component: a psychic vulnerability which might contribute to the progress of the disease, and more clearly so in patients with secondary Raynaud's phenomenon than in patients with primary Raynaud's phenomenon, as confirmed by the so-called psychic fragility" score used to quantify the efficiency of mental functioning. These psychological features were unrelated to age. The profile of patients with secondary Raynaud's phenomenon is close to pattern C described as possibly having a prognostic value in proliferative or autoimmune diseases.

Adult↗
PubMed1986

[Hemodynamic study, under hot and cold conditions, of the digital artery in arterial hypertension and the effects of cardioselective and non-cardioselective beta blocker treatment].

The finger systolic pressure of 25 healthy subjects and 23 hypertensives was studied by plethysmography at 30 degrees, 15 degrees and 10 degrees centigrade. The hypertensive group was given equipotent doses of either Metoprolol or Propranolol in accordance with a double-blind cross-over protocol including a washout period. The fall in systolic pressure between the brachial artery in the upper arm and the digital artery was significantly increased in the hypertensive group as compared to healthy controls; the rise persisted under hot and hyperemic conditions and remained constant during both betablocker treatments. In the hypertensive group digital arterial tone increased under cold conditions before any treatment; this abnormality did not vary under Metoprolol but intensified significantly under Propranolol. Finger plethysmography made it possible to show and quantify the peripheral vascular repercussions of hypertension on the digital artery and evaluate the changes induced by treatments. It also helps to clarify the physiopathology of certain side effects caused by betablockers and might to some extent help in the choice and the survey of treatment and in the subsequent follow-up.

Adrenergic beta-Agonists↗
PubMed1979

[Does the hepatitis of secondary syphilis exist? Two cases (author's transl)].

Two patients are presented as new cases of secondary syphilitic hepatitis. The closely resemble descriptions in the literature with the same clinical and laboratory "profile" and the same course spectaculary influenced by anti-syphilitic penicillin therapy. The presence of treponemes in the liver, which would definitely confirm the diagnosis, was not demonstrated. This is a particularly important diagnosis, which should not be missed since it leads to treatment of fundamental importance to the patient's future.

Adult↗
PubMed1979

[Raynaud's phenomenone: prospective study of 100 cases (author's transl)].

A prospective study of 100 consecutive patients hospitalised with a Raynaud phenomenone is presented. In 82 patients, a precise etiology was pound, most often a collagen disease (50 cases) and amongst this group generalised scleroderma was the most commun (n = 37). Other etiologies were very divers: inflamatory artertis, atheroma, local mecanical causes, emboligenic. In 18 patients, no etiology was found: the age, the sex, the context and the benign cours in this patients was such that a diagnosis of idiopathic Raynaud's phenomenone. This results lead to the suggestion of a method for the investigation of Raynaud's phenomenone. The consequences are therapeutic, the etiological context foring the base of the treatment prescribe.

Adult↗
PubMed1979

Chromosome breakage and xenotropic C-type virus in embryonic cultures from New Zealand black mice.

A considerable increase in chromatid and chromosome breaks, as well as excessive fragmentation and "pulverization" of whole metaphase plates was observed in embryonic fibroblast cultures from New Zealand black mice. A C-type RNA virus with a xenotropic host range was isolated from the supernatant fluid of co-cultures of NZB cells and heterologous permissive cells (SIRC cell line). One of the NZB cultures produced this virus without amplification by co-cultivation after spontaneous transformation of the cells. NZB cells are supposed to lack normal restriction of complete xenotropic virus expression and to release this endogenous virus spontaneously at a high level. It is hypothesized that the excessive chromosome damage observed in these cell cultures is related to the permanent production of virus, thus indicating a chromosome breaking effect of endogenous viruses.

Age Factors↗
PubMed1979

[Thrombosis of the portal and superior mesenteric veins in a patient with a congenital and familial deficiency in antithrombin III (author's transl)].

Thrombosis of the visceral veins is an extremely rare condition in cases of congenital and hereditary deficiency of antithrombin III, associated with recurring venous thorbosis of the limbs. The authors report such a case in a man of 40 years of age, who had this deficiency, associated with thrombosis of the portal and superior mesenteric veins and a portal cavernoma. They stress the frequent association of recurring peripheral vein thrombosis, portal vein thrombosis in adults, and thrombosis of the mesenteric vein, and the importance of systematic measurements of antithrombin III levels in these pathological conditions.

Adult↗
PubMed1978

[Relationship between digital necrosis of the upper limbs and malignant conditions (author's transl)].

The authors report six new cases of necrosis of the fingers occurring during the course of a malignant condition. None of the patient was suffering from any other disease which could explain the digital necrosis. They discuss the mechanism of the relationship between the two conditions : blood hyperviscosity, thrombocytosis, polycythaemia, cryoglobulin and the production of immune complexes. The particular role of bleomycin is mentioned. The possibility of a true paraneoplastic syndrome is suggested.

Adult↗
PubMed1978

[Giant cell arteritis and takayasu's disease: histopathological criteria (author's transl)].

Both of these arterial diseases may involve the aorta and the major arterial trunks. Two cases of subclavian involvement are used to contrast them from a histopathological standpoint. In giant cell arteritis, the lesions affect above all the internal elastic layer and the inner part of the media, destroyed by an inflammatory infiltrate with giant cells. In Takayasu's disease, the lesions involve the adventitia, the site of fibrosis and of inflammatory islets with the vasa vasorum at the centres. Involvement of the media is predominantly in its outer part, the internal elastic layer being intact. A histopathological definition of these arterial diseases may be envisaged on the basis of these facts.

Adult↗
PubMed1978

[Thrombolytic treatment of arteriopathies].

Systemic streptokinase has shown its effectiveness in the treatment of recent arterial obstruction of the limbs. The haemorrhagic and embolic complications of this type of treatment nevertheless limit its indications. Streptokinase should be reserved for acute thromboses present for less than two months, and responsible for severe ischaemia without the possibility of surgical treatment. The intra-arterial administration of urokinase limits the risks of systemic fibrinolysis, though the effectiveness of the therapeutic protocols proposed has yet to be demonstrated.

Arterial Occlusive Diseases↗
PubMed1978

Salivary immunoglobulins in progressive systemic sclerosis.

A study of salivary immunoglobulins revealed the presence of IgM in 11 out of 17 patients suffering from progressive systemic sclerosis. The presence of IgM was frequently accompanied by an increase in IgA and less often by IgG. Immunofluorescence examination of labial biopsies showed comparable modifications in the immunocyte populations; the presence of IgM cells, sometimes in large numbers, and an increase in IgA and IgG cells. All patients with a nodular lymphoplasmocyte infiltration of the minor salivary gland of the lip have salivary IgM. The presence of IgM in the saliva is a diagnostic criteria of Sjögren's syndrome. The absence of a correlation between immunoglobulin concentrations in the saliva and the serum and correlation between the salivary IgM concentration and the number of IgM immunocytes, demonstrate that the presence of IgM is related to the glandular synthesis of this enzyme.

Adult↗