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Biomedical subjects

E Huraj

Publications and source records attributed to E Huraj.

At least 19 recordsLinked to original sources
PubMed1990

[Is it possible to objectively study back pain in orthopedic practice?].

The authors concentrate on vertebral diseases in the polyclinic practice, they emphasize their sociomedical significance. The statistical data are presented to document the number of examinations and the prevalence of work inability during the last 5 years which has an increasing tendency. To emphasize the problem of the objectification of the vertebral painful syndrome at the polyclinic they present two case reports, draw attention to the dissension of views of polyclinic specialists as concerns etiopathogenesis of vertebral diseases and related to it the problem of objectification with regard to work ability. According to the authors' view the vertebral syndrome can be precisely objectified on the basis of a profound functional examination. This important sociomedical problem of vertebral diseases in relation to work ability could be improved from the organizational view point also by appointing one physician at the polyclinic who would pursue this task comprehensively substituting a number of specialists who at present have to deal with it as part of their duties.

Adult↗
PubMed1990

[Selected immunologic indicators in malignant bone tumors].

In patients with the malignant tumor of bone (17 osteosarcomas, 8 Ewing tumors) longterm observations were made, and namely at the beginning of the disease, after the surgical removal of the tumor, during chemotherapy and in the terminal phase of the disease. The observations concentrated on the following selected immunology parameters: active lymphocytes T, lymphocytes T, lymphocytes B, large granular lymphocytes, IgG, IgA, IgM and circulating immune complexes. In non-treated patients prior to diagnosing the disease, reduction of active lymphocytes T was found out while the total lymphocytes T remained unchanged. However, no significant differences were found out between benign and malignant tumors. The surgical removal of the tumor results in the change in imunologic indicators, the increase of active lyphocytes T, lymphocytes T and the decrease in the circulating immune complexes. The change is of temporary nature, the subsequent deterioration is caused by both the progression of the disease and chemotherapy. The values of immunoglobulins and lymphocytes B fluctuated during the whole course of the disease in physiological levels. The observation of active lymphocytes T and lymphocytes T can be used for monitoring of the immunosuppression in cytostatic treatment. The levl of IgG is differentially diagnostically used to distinguish between the tumor and inflammatory processes.

Adolescent↗
PubMed1989

[Problems in the diagnosis of Ewing's sarcoma].

The aim of the work was to analyze by the method of retrospective study the difficulties in diagnosing the Ewing sarcoma at the Department of Orthopaedic of the Teaching Hospital in Bratislava in the years 1967-1987. The authors found out that there were diagnosticated 28 cases of the Ewing sarcoma, the boy-girl ratio was: 1:1. Most frequently it occurred between 12 and 18 years of age. Apart from clinical examination they use classical sciagraphy, macropictures, tomography, arteriography, gammagraphy of the skeleton, computer tomography, lymphography, histological, and electron microscopic examination. In the conclusion the authors point out that the timely treatment may be ensured by a precise and demanding screening carried out by pediatricians, practitioners in charge of adolescents and orthopaedists and by further reduction of the time interval necessary for performing all above mentioned examinations. The care of the Ewing sarcoma is the responsibility of suitably equipped special centres of bone oncology.

Adolescent↗
PubMed1989

[Arteriography, lymphography, gammagraphy and computer tomography in the diagnosis of musculoskeletal tumors].

The authors emphasize the importance of early and exact diagnosis of musculoskeletal tumours of the extremities and spine. This aim cannot be achieved by common biochemical, haematological and X-ray examinations. Therefore the authors recommend to use already during the initial examination of the patient a combination of classical roentgenography, arteriography, possibly lymphography, gammagraphy and computed tomography. The authors present a detailed account of experience with the application of the above diagnostic methods in 146 patients. On arteriograms of 37 patients dislocated main arteries were found 16 times, blood lakes 20 times. Lymphography revealed metastatic affection of regional lymph nodes in 21% of all patients, most frequently in bone reticulosarcoma and in synovial sarcoma. All-body gammagraphy helped to make the localization and assessment of size of the tumour more accurate, in two-thirds of the patients it was larger when visualized by this method than on native roentgenograms. In 3 of 14 Ewing sarcomas all-body gammagraphy revealed a polyostotic localization of the tumour. Computed tomography revealed the extent of infiltration and destruction of bone and soft tissues in pelvic and spinal tumours.

Adolescent↗