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Biomedical subjects

E I Chesmochakova

Publications and source records attributed to E I Chesmochakova.

4 recordsLinked to original sources

[Catecholamine complex-adrenoreactive system of various subtypes in various forms of bronchial asthma in children].

During the acute period of diverse forms of bronchial asthma in children the following alterations were detected in catecholamine metabolism and in various subtypes of the adrenoreactive system: an increase in urinary excretion of catecholamines, especially of adrenaline, as well as activation of catechol-O-methyl transferase; a decrease (or even absence) of beta 2-adrenoreactive system sensitivity, a decrease in beta 1-reactivity, while sensitivity of alpha 1-adrenoreactive system was increased (in the infectious-allergic form of the disease) and alpha 2-reactivity was unaltered. The uncoupling between catecholamines and various subtypes of the adrenoreactive system appears to occur during the acute period of bronchial asthma.

Adolescent↗

[Changes in the sensitivity of the adrenoreactive systems of various subtypes in rheumatic fever in children].

Distinct and generalized decrease in sensitivity of alpha 2-adrenoreactive system, pronounced decrease of beta 1- and beta 2-but not of alpha 1-adrenoreactivity were observed in children with acute rheumatic fever. After cupping of the rheumatic attack and restoration of circulation functions impairments of the alpha 2-adrenoreactivity (but not of beta 1- and beta 2-adrenoreactivities) were decreased however without complete normalization. Absence of a number of sympathogenic reactions appears to occur due to impairment of the adrenoreactive system sensitivity even though accumulation of catecholamines as found in biological fluids, as a result of which catecholamine-effector uncoupling elevated.

Adolescent↗

[Study of the alpha2-adrenoreactive system in man].

A new approach for evaluation of the sensitivity of alpha 2-adrenoreactive system in men, based on main effects of clonidine, is developed. It may be used in investigation of both physiological and pathological processes in human body.

Adolescent↗