[False acute abdomen as a mask of some endocrine diseases].
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Biomedical subjects
Publications and source records attributed to E I Kovalenko.
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A model system was developed to study the role of cell surface oligosaccharides in cytotoxicity mediated by natural killer (NK) cells. Polymeric glycoconjugates Glyc-PAA-PE and Glyc-PAA(Flu)-PE (where Glyc is the 3-aminopropyl Le(x) residue, PAA is the poly(N-2-hydroxyethylacrylamide) matrix, Flu is the residue of a fluorescein derivative, and PE is the phosphatidylethanolamine residue) were synthesized, and their association with the membranes of living K562 cells was studied.
A new method is proposed to analyse dependencies in point processes, which takes into account specific character of neuronal activity. Simulation modelling of neuronal network revealed that the estimated weight of connection depends monotonically on the value of the model synaptic strength. In contrast to the crosscorrelation, the method allows for nonlinear interconnections and does not require point processes to be stationary and samples to be large. Examples are presented of the method's application to neurophysiological data analysis.
Statistical methods were used to study types of background activity (BA) of neostriatum neurons. Dependence of the crosscorrelation function on the BA type and on a distance between the neurons was examined in acute experiments on rats (one group was immobilized with d-tubocurarin, the other was under nembutal anesthesia). It is shown that BA according to the shape of the autocorrelation and crosscorrelation functions can be classified into five types (I.1, I.2, I.3, II.1, II.2). Pronounced differences in the crosscorrelation function were found between the neurons with grouped BA (I.1, I.2) and the neurons with unitary BA (II.1, II.2). Differences in the crosscorrelation function between close and distant (300-500) microns) neurons were also found.
It was shown that neutrophil aggregation is caused by all lectins with different specificity for carbohydrates but generation of active oxygen forms is induced only by some lectins. Polyspecific lectins-erythroagglutinin and phytohemagglutinins have the greatest activity in relation to both processes.