PubMed Health⌕ Search

Biomedical subjects

E I McNaught

Publications and source records attributed to E I McNaught.

5 recordsLinked to original sources
PubMed1988

Grid photocoagulation improves reading ability in diffuse diabetic macular oedema.

Forty-eight patients with diffuse diabetic macular oedema were treated with perifoveal blue/green Argon 'grid' laser photocoagulation. Clinical assessment of patients was supported by serial fluorescein angiography. Patients were followed up for one year after treatment, and a two year follow-up was obtained in 29 patients. Statistical analysis showed no significant improvement in distance acuity, but demonstrated clear benefit as regards reading ability.

Adult↗
PubMed1981

The permeability of the posterior blood ocular barrier after xenon photocoagulation: a study using fluorescein labelled dextrans.

Xenon photocoagulation burns in the rabbit fundus were studied angiographically with fluorescein labelled dextrans of molecular weights in the range 3000 to 150 000. Recent photocoagulation burns showed dye leakage to all molecular weights used. Angiograms 2 days after burns had been produced showed leakage of dextrans of molecular weights up to and including 70 000 but no leakage of dextran of 150 000 molecular weight. At 7 days after photocoagulation healed burns remained permeable to dextrans of molecular weight 3000 or 20 000, but in the majority of eyes such burns did not leak dextrans of over 40 000 molecular weight. The clinical significance of the selective nature of photocoagulative damage to the posterior blood ocular barrier is discussed.

Animals↗
PubMed1977

Effect of photocoagulation on the barrier function of the pigment epithelium. II. A study by electron microscopy.

The healing of retinal photocoagulation burns and their permeability to colloidal carbon and horseradish peroxidase was studied by electron microscopy. Recent burns showed disruption of intercellular junctions in the pigment epithelium. By 2 days there was infiltration of the burn by proliferating pigment epithelial cells, and by 7 days the burn was composed of a mass of interconnected cells of pigment epithelial and Müller cell origin. Fresh photocoagulation burns result in complete disruption of the blood-ocular barrier, permitting particles as large as colloidal carbon to pass between disrupted pigment epithelial cells. Healed photocoagulation burns remain permeable to smaller tracers such as horseradish peroxidase.

Animals↗