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Biomedical subjects

E I Miller

Publications and source records attributed to E I Miller.

17 recordsLinked to original sources

Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration.

OBJECTIVE: This paper describes the clinical and imaging characteristics of seminoma complicating intraabdominal testes in three patients who had a history of negative findings from surgical exploration of the inguinal canal and scrotum. CONCLUSION: Because inguinal surgery for cryptorchidism may fail to disclose intraabdominal testes, surgery that has negative findings should be followed up by a close examination of the abdomen. Seminomas arising from an intraabdominal testis can be large and asymptomatic or may simulate other diseases. Torsion may occur and occasionally appear as acute abdomen. The imaging features can be nonspecific, and the history of cryptorchidism may not be provided. Awareness of the clinical and imaging features of neoplasms involving undescended intraabdominal testes is important for appropriate diagnosis and therapy.

Abdomen↗

Ultrasonographic detection of ureteral jets in normal pregnancy.

OBJECTIVE: Our purpose was to determine the impact of normal physiologic urodynamic alterations of pregnancy on the detection of ureteral jets into the bladder with use of transabdominal color Doppler ultrasonography. STUDY DESIGN: We conducted a prospective cohort study of 125 healthy asymptomatic gravid women without any history of past or current renal disease, all with singleton pregnancies between 13.4 and 37.7 weeks' gestation. Right and left ureteral jets were recorded over a 5-minute period with use of color Doppler transabdominal ultrasonography and a full bladder. Each kidney was graded by the severity of the hydronephrosis. No hydronephrosis was grade 0, mild hydronephrosis was grade 1, and moderate hydronephrosis was grade 2. There were no cases of severe hydronephrosis. RESULTS: There were 56 grade 0 cases on the right versus 93 grade 0 cases on the left (p < 0.0001), 53 versus 30 grade 1 cases (right vs left, p < 0.003) and 16 versus 2 grade 2 cases (right vs left, p < 0.0009). In the subgroup where both kidneys were grade 0 the mean number of right ureteral jets 5 mm was 14.7 versus 15.1 for the left ureteral jets (p = 0.73). In the grade 1 subgroup mean right versus left ureteral jets was 15.4 versus 16.6 (p = 0.65). For the grade 2 subgroup mean right versus left ureteral jets was 15.5 versus 21.0 (p = 0.32). There were 4 of 125 unilateral absent ureteral jets on the right versus 0 of 125 on the left (p = 0.122). CONCLUSION: Our data demonstrate that ureteral jets can be readily detected during pregnancy independent of the gestational age. In addition, it does not appear that the physiologic urodynamic alterations of pregnancy affect the frequency or symmetry of ureteral jets. Thus identification of ureteral jets can be used in the workup of suspected urolithiasis in pregnant patients.

Cohort Studies↗

Sonographically detected fetal choroid plexus cysts. Frequency and association with aneuploidy.

Over a 22-month period, 1045 second-trimester pregnancies were evaluated with ultrasound for the presence of choroid plexus cysts. The frequency of fetal choroid plexus cysts was 3.6% (38/1045). The outcome of the 38 fetuses possessing choroid plexus cysts was as follows: One fetus had triploidy, an occurrence not previously reported; one fetus had hydrocephalus and a normal karyotype; the other 36 fetuses were born normal. Our data were combined with those of previously reported series of fetal choroid plexus cysts to determine if chromosomal analysis is necessary in all fetuses possessing a choroid plexus cyst.

Adult↗

Sonographically demonstrated intra-amniotic hemorrhage following transplacental genetic amniocentesis. Frequency, sonographic appearance, and clinical significance.

Over a 9-month period, 11 transplacental amniocenteses were performed. Following completion of amniocentesis, intra-amniotic hemorrhage occurred in all 11 cases. Amniotic masses and intra-amniotic strands occurred in three cases as a result of intra-amniotic hemorrhage. The 11 pregnancies in which transplacental amniocentesis were performed were uncomplicated, and they resulted in normal infants. Transplacental amniocentesis can yield unusual sonographic appearances but does not appear to have an adverse effect on pregnancy outcome.

Adult↗

Hemorrhagic cholecystitis. Sonographic appearance and clinical presentation.

In this retrospective study of 19 patients with hemorrhagic cholecystitis, 14 (74%) patients demonstrated one of the following unusual sonographic features: focal gallbladder wall irregularity; intraluminal membranes; coarse, nonshadowing, nonmobile intraluminal echoes. The clinical presentation of these cases (abdominal pain, 100%; leukocytosis, 74%; fever, 63%) is identical to the classic presentation of acute cholecystitis. Overt gastrointestinal bleeding did not occur.

Acute Disease↗

Evaluation of extratesticular findings in scrotal neoplasms.

The significance and incidence of skin thickness, hydroceles, and epididymal size were evaluated in cases of testicular neoplasm. Skin thickness is unreliable and should not be used to differentiate pathological conditions without standardizing technique. Small hydroceles are common in scrotal neoplasms. Epididymal enlargement was seen in many cases of testicular neoplasia and cannot be used alone as a criterion to differentiate malignant from nonmalignant states.

Dysgerminoma↗

Portal vein invasion demonstrated by ultrasound.

Two patients evaluated by ultrasound for abdominal masses were found to have thrombus within their central portal veins. Their cases are presented with angiographic correlation. Both are proven cases of hepatocellular carcinoma. The importance of evaluation of the portal vein in patients with liver neoplasms is discussed.

Aged↗

Persistant corpus luteum cyst of pregnancy: sonographic evaluation of cause of third trimester bleeding.

Corpus luteum cysts are frequently observed in pregnant patients evaluated with diagnostic ultrasound. They are usually regarded as incidental findings because of their limited size and usual pattern of regression by ten weeks. The presence and persistence of larger corpus luteum cysts or other extrauterine masses may complicate pregnancy. A case of a large persistent corpus luteum cyst associated with third trimester bleeding is presented.

Adult↗

The atrophic postmenopausal uterus.

The size of postmenopausal uterus varies, but after 65 years of age, it routinely appears atrophic. A pelvic mass in this age group should not be assumed to be within the uterus unless a careful search excludes an atrophic uterus. Single sweep longitudinal ultrasound sections are the best method of localizing a small uterus, but sometimes gain settings must be varied to demonstrate the organ.

Aged↗