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Biomedical subjects

E I Vorob'eva

Publications and source records attributed to E I Vorob'eva.

8 recordsLinked to original sources
PubMed2005

[Analysis of group B streptococcal gene scaAB encoding the protein involved in adherence and aggregation].

The portion of group B streptococcal (GBS) sequence encoding the ABC transport system was cloned and sequenced. The genetic region under study included scaAB gene, which was capable of encoding for putative adherence and aggregation factor, and scaR, which was encoding for putative represser. After the insertional inactivation of scaAB gene on the GBS chromosome streptococci increased the tendency for aggregation. The level of GBS adherence to vaginal epithelium was also different after scaAB inactivation. GBS sea operon was compared to similar ABC encoding bacterial operons.

Adhesins, Bacterial↗
PubMed2002

[C-reactive protein as possible early prognostic marker of restenosis development in coronary artery stents].

AIM: To study possible link between inflammatory response of the body to stent implantation and development of instent restenosis. METHODS: C-reactive protein (CRP) was determined in 24 patients subjected to coronary stenting. Coronary angiography was repeated in 7.1-/+0.68 months after initial procedure. RESULTS: At repeat angiography positive results of stenting persisted in 18 while restenosis developed in 6 patients. All patients had increased CRP levels on days 2-3 after stenting. Day 2 CRP levels were higher in patients with than without restenosis (28-/+4.22 mg/l and 14.17-/+2.14 mg/l, respectively, p<0.05). CRP levels tended to normalize by day 5. CONCLUSION: Coronary artery stenting in patients with angina pectoris is associated with transitory elevation of CRP level. Day 2 CRP >or=24 mg/l with high degree of probability predicts restenosis in remote period.

Adult↗
PubMed1981

[Evolution of cartilage in the skeletons of ancient anamniotes].

Owing to discoveries of ancient fossils of the Anamnia it was revealed that endo and exoskeletal tissue have an independent history of development. At early evolutional stages, the exoskeletal tissues were connected by various transitions and were at the stage of incomplete differentiation. During evolution variability of these tissues decreased; this resulted in disappearance of aspidin from the tegmentum, and dentin remained only in some primitive groups of fishes (sharks, Latimeria chalumnae, Lepidosteus osseus), while in most vertebrates the exoskeleton was formed exclusively from the osseous tissue. In the endoskeleton the cartilage evolutionally preceded the bone. It is rather difficult to draw any border between the calcified cartilage and the bone in the ancient vertebrates. When an osseous tissue healing occurs at some pathological processes in the vertebrae, a primitive state of the endoskeletal tissue is reproduced. Secondary progressive cartilage development during evolution in the anamnia is considered as a result of negative anabolism and connected with a slowed morphogenesis. Chondrification evidently increases plastic possibilities of the endoskeletal structures.

Animals↗
PubMedDate not supplied

[The problem of organism integrity and its perspectives].

The organism integrity in onto- and phylogenesis is considered as an initial element of biosphere integrity and its evolution at the eukaryotic level. The Schmalhausen's concept of organism integrity is discussed in the context of his original strategy of evolutionary synthesis and his works on stabilizing selection. The perspectives of investigations on the problem of integrity and development of the principle of dynamic stability in contemporary evolutionary biology as integrating factors are discussed.

Animals↗
PubMedDate not supplied

[I. I. Shmal'gauzen's concept of the evolution of ontogeny].

The concept of evolution of ontogenesis by I. I. Shmal'gauzen is presented as a result of reviewing some of his theoretical works. This concept appears to be the most consistent development of classical darwinism on the basis of a basically new (as compared with synthetic theory of evolution) evolutionary-synthetic approach. This latter has been based on the idea of the organism integrity in onto- and phylogenesis and the involvement of the organismic level (ontogenesis), together with the population and biocoenotic ones, in the evolutionary process as a whole.

Adaptation, Physiological↗