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E Ia Amirov

Publications and source records attributed to E Ia Amirov.

4 recordsLinked to original sources

[Formation of specifically transducing lambda alpha g-particles. I. Relationship between the quantitative composition of transductants and the type of inductive activity].

To study the formation of specifically transducing particles, different physical and chemical prophage-inducing factors (spontaneous induction, UV and roentgen irradiation, treatment with mitomycin C and nalidixic acid). Each kind of induction used in this study was shown to bring about the formation of transducing particles. The kind of inducing action influenced the qualitative composition of transductants. DNA ruptures caused by inducing factor may be supposed to play the main role in the formation of specifically transducing lambda dg-genomes.

Bacteriophage lambda↗

[Formation of specifically transducing lambda dg-particles. II. Relationship between the transduction rate, the qualitative composition of the transductants, and the dose of the inducing agent].

The formation of specifically transducing lambda dg-particles in E.coli strain W3110 (lambda) due to the effect of different doses of UV irradiation was studied. A sharp increase in both the absolute number of transductants and the relative transduction frequency was found to occur as the dose of UV irradiation increased. On achieving definite doses this relationship became almost direct. At higher doses similarity was observed in the kinetics of a decrease in the absolute number of transductants and in active phage titers. As the dose increased further, a sharp increase in the percentage of heterogenoue transductants occurred. The conclusion that the formation of specifically transducing lambda dg-particles is due to the effect of the inducing factor on the DNA of lysogenic cells has been made.

Bacteriophage lambda↗