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Biomedical subjects

E Ia Drukin

Publications and source records attributed to E Ia Drukin.

17 recordsLinked to original sources

[The role of conservative resection in surgical treatment of patients with lung cancer].

The immediate and end results of 56 limited segmental resections of the lung (palliative--12 and radical--44) for cancer were studied. Postoperative mortality was 6.8% and five-year survival--50.0%. It is suggested that surgery for peripheral cancer without regional metastasis should be recommended for tumors under 2 cm in diameter in poor-risk patients. The procedure should be preferred for treatment of adenocarcinoma.

Aged

[Evaluation of diagnosis and treatment of various clinico-anatomical forms of lung cancer].

Among 3898 cases of primary lung cancer registered in Leningrad within 1985-1986, central cancer clearly predominated (61.9%). Central/peripheral cancer ratio was 1.6:1. The most common procedure used for treatment of central lung cancer was pneumonectomy (74.6% of cases) and lobectomy--for peripheral cancer management (85.7%). Significant differences in approach to diagnosis and surgical treatment of these pathologies were established. It seems unfeasible to increase resectability of central lung carcinoma by extending surgery. Such tumors should be diagnosed at the stage of segment involvement. However, prophylactic photo-roentgenography does not assure early detection of central lung cancer. Organization of lung cancer detection in Leningrad needs to be improved.

Aged

[Diagnosis of central cancer of the lungs].

Data on 396 patients with central cancer of the lung admitted to the thoracal department of the Petrov Research Institute of Oncology and the City Oncological Dispensary in 1985-1986 are presented. In 94 of them (23.7%) the disease was diagnosed by prophylactic roentgenofluorography, in 302 (76.3%)--in consultation with a doctor. Operability of the patients of the first group was somewhat higher than in those of the second group. During the two years under analysis the roentgenofluorography detected central cancer of the lung in 266 patients (11%). Radical operations were performed in 48 patients (18%), while in patients consulted by doctors after the appearance of clinical symptoms of the disease, resectability made up 13.3%. Main efforts should be directed to the active detection of central cancer of the lung in patients who addressed the polyclinic for lung symptoms.

Adult

[Factors determining the status of the surgical care of lung cancer patients in a large industrial center].

The report deals with the dynamics of resectability in 30,456 patients with lung cancer registered in Leningrad in 1968-1985 versus such important characteristics of morbidity as yearly increase in tumor incidence and increasing age of patients. It also discusses possible total levels of operability and resectability as well as those in different age groups versus sex, diagnostic, functional and biological characteristics and patients' refusal to be operated. Standards of surgical treatment for lung cancer in certain localities should be evaluated versus expected level of resectability, and age and sex.

Adult

[Histological structure and tumor size as prognostic factors in the surgical treatment of patients with peripheral lung cancer].

An analysis of long-term (5 years) results of treatment of 444 patients with peripheral lung cancer has shown that in adenocarcinoma the tumor size is of no significance for prognosis of the disease while in squamous cell carcinoma of more than 5 cm diameter the prognosis is significantly worse (almost 2 times). Since the squamous cell carcinoma is known to be the less biologically active form of lung carcinomas the authors consider that the main task is the organization of measures for early detection of this kind of tumors less than 5 cm in diameter.

Adenocarcinoma

[Combination of primary lung cancer with extrapulmonary carcinomas].

An analysis is given of 50 observations of lung cancer associated with cancer of other organs. Lung cancer was preceded by cancer of another organ in 33 patients (66%), cancer of another organ developed after lung cancer had been cured--in 6 (12%), and synchronous involvement was noted in II (22%). An average interval between radical surgery for lung cancer and subsequent tumor growth in another organ was 6.2 years. Among patients with synchronous carcinomas the association with laryngeal cancer (4) and cancer of the stomach (4) was most frequently noted. The principles of treatment in patients with synchronous carcinomas are described.

Adult

[Diagnosis of cancer of a peripheral bronchus].

Among 308 patients with peripheral cancer of the lung in 132 patients (42.9%) tumor was found during fluorographic examination. The operability in these patients was higher, the size of the tumor was somewhat less, metastases in intrathoracic lymph nodes in radical surgery occurred more rarely. However, these differences were not significant enough to regard patients with asymptomatic peripheral cancer as being in a better condition, compared with those having a symptomatic disease. It is concluded that a fluorographic survey, as it is at present time, fails to reveal early form of peripheral lung carcinoma.

Adult