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Biomedical subjects

E Ia Tkachenko

Publications and source records attributed to E Ia Tkachenko.

At least 19 recordsLinked to original sources
PubMed2005

[Effect of rapid and slow cooling on thermoregulatory responses in hypertensive and normotensive rats after calcium administration].

The effect of iontophoretic administration of calcium ions to skin in the area of cold stimulus application on the thermal thresholds and the magnitude of cold defense responses in normotensive Wistar and hypertensive ISIAH rats was studied. In thermoneutral conditions, administration of calciumions wos without effect on the measured thermoregulatory parameters. Under the effect of calcium, the thresholds of all the thermoregulatory responses to cooling (such as heat loss, oxygen consumption, shivering) are lowered and the values of heat loss and shivering thermogenesis are considerably increased. The effects of calcium on thermoregulatory responses depend on the rate of cooling. All changes are more expressive in hypertensive rats. The increased sensitivity of hypertensives to calcium suggests that change in their calcium metabolism may be a cause of the observed shifts in the thermoregulatory response to cold.

Animals↗
PubMed1991

[Effect of adaptation to cold and physical training on heat emission during muscle work].

People, for a long time exposed to cold and physical training or cold only, exhibit strengthening of thermal regulatory reactions aimed at the preservation of heat in the body in the state of rest, as well as during muscular tension. Adaptation of the organism to cold in the situation of limited motor activity lead to the increase of the thickness of the body "cover" under the conditions of rest in the cold due to the decrease of the temperature of skeletal muscles, while physical training in the cold facilitates stabilization of muscular temperature and, correspondingly, lessening of the thickness of the "cover". At the initial stage of muscular activity thermal regulatory reactions of the organism are aimed at the decrease in heat emission, which promotes accelerated heating of the muscles.

Adaptation, Physiological↗
PubMed1985

[Thermoregulatory effect of beta-adrenoreceptor block in the cold-adapted rat at rest and during exertion].

Inderal does not affect the thermoregulatory system in thermoneutral conditions. Blockade of beta-adrenoreceptors at 6 degrees C decreases the oxygen consumption in cold-acclimated rats and reduces it down to the level of control animals. Cold-acclimated rats have the same level of work hyperthermia at different ambient temperatures (26 degrees C, 6 degrees C) and under inderal injection. Control animals can only the same in warm environment.

Adaptation, Physiological↗
PubMed1978

[Effect of adaptation to hypoxia on the working capacity and energy of skeletal muscles].

The authors studied the working capacity and heat formation of the skeletal muscles during contraction in rats--control and those adapted to hypoxia. The force of contraction, the work and fatigueability of the muscles, as well as elevation of the muscle temperature as a result of contraction were determined under conditions of indirect muscle electrostimulation. Hypoxia adaptation failed to influence the force of muscle contraction and the work performed. However, hypoxia led to reduction of the temperature effect of the muscle contraction per unit of the work performed. This pointed to increase of the efficiency of the muscle work in hypoxia adaptation. Fatigueability of the muscles in "hypoxic" rats was elevated. Changes in the energy of the muscle contraction in hypoxia and cold adaptation were different.

Adaptation, Physiological↗
PubMed1976

[Work capacity of skeletal muscles and energetics of muscular work during adaptation to cold].

After the cold adaptation muscle contraction and the working capacity decreased. However, the muscles of the adapted to cold rats are able to save the initial power for a longer time. The muscular work of adapted to cold rats involves a greater expenditure of energy as compared with the control rats. Changes of the working capacity of skeletal muscles in control rats after noradrenalin administration are similar to those occurring in adapted to cold rats.

Adaptation, Physiological↗
PubMedDate not supplied

[The functional modifications under the long-term adaptation to cold].

The data on modifications and interrelation of the afferent and efferent parts of the thermoregulatory system under the long-term adaptation to cold are presented. The body of data evidences for the important role of the thermoreceptors in the adaptive changes of the cold-defense responses.

Acclimatization↗