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Biomedical subjects

E J Berman

Publications and source records attributed to E J Berman.

11 recordsLinked to original sources
PubMed1991

Right ventricular hypertrophy detected by echocardiography in patients with newly diagnosed obstructive sleep apnea.

We used polysomnography, echocardiography and ventilatory measurements to study 50 patients suspected of having OSA to determine a link to RVH. Twenty-eight patients (56 percent) had OSA and 20 (71 percent) of those had isolated RVH. We evaluated patients with RVH and divided them into two groups, those with apnea and those without apnea. The patients with sleep apnea were younger, weighed more, had greater BSA and had lower average oxygen saturations during the sleep study period. We divided the group with apnea into those with RVH and those without it. Those patients with RVH had a higher AI, longer average apnea time, a greater duration of longest apnea and a lower average oxygen saturation for the period of the sleep study. In addition, those with RVH had a lower average oxygen saturation during each apneic episode with a p value equaling 0.09.

Adolescent↗
PubMed1989

Recall and eye tracking study of adolescents viewing tobacco advertisements.

The warning on tobacco advertisements was required by the federal government, presumably as a health message to educate the public about the risks associated with tobacco use. Despite its potential public health role, there have been few published studies on the effectiveness of these warnings as a health message. The present study used well-accepted market research methods to examine adolescent viewing of tobacco advertisements. Sixty-one adolescents participated in the study. Eye tracking was used to study how participants viewed five different tobacco advertisements. The average viewing time of the warning amounted to only 8% of the total advertisement viewing time. In 43.6% of cases, the warning was not viewed at all. Following the advertisement viewing, participants were asked to identify the observed warnings within a list that included other simulated warnings. Subjects did only slightly better than random guessing in this test of recognition. Using market research criteria, the federally mandated warning must be viewed as an ineffective public health message in so far as adolescents are concerned.

Adolescent↗
PubMed1986

Chromosomal mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1.

A panel of 42 rodent X cat somatic cell hybrids segregating individual cat chromosomes in different combinations was used to assign five isozyme structural loci to cat chromosomes. The feline homolog for glutathione reductase (GSR) was mapped to chromosome C2. Adenosine deaminase (ADA) and inosine triphosphatase (ITPA) were located on chromosome A3. Lactate dehydrogenase-A (LDHA) and acid phosphatase-2 (ACP2) were reassigned to chromosome D1. Localization of these genes increases the known feline genetic map and extends the known syntenic homologies between the cat and other mammalian species.

Adenosine Deaminase↗
PubMed1985

Spontaneous ocular shedding of HSV-1 in latently infected rabbits.

The unscarified corneas of rabbits were inoculated with 50 microliter of 2-4 X 10(6) PFU/ml of herpes simplex virus, type 1 (HSV-1), McKrae strain in 10 separate experiments over a 12-month period. Sixty of 104 (57.7%) rabbits survived to postinoculation (PI) day 20. These sixty rabbits were swabbed with dacron-tipped swabs for twenty consecutive days (PI days 20-39). The tear film collected on the swabs was immediately placed in tissue culture tubes with confluent primary rabbit kidney (RK) cell monolayers. The RK monolayers were monitored for cytopathic effects indicative of HSV-1. Fifty-eight of the sixty rabbits (96.7%) inoculated had at least one positive episode. Ninety-three of the 120 eyes (77.5%) of the latently infected rabbits had at least one positive episode. Virus was detected in 72 of the 93 positive eyes (77.4%) between PI days 20 and 29 and in 21 of the 93 positive eyes (22.5%) between PI days 31-39. A total of 2400 swabs were taken and 324 were positive (13.5%). All of the 58 positive rabbits were used later for ocular induction of HSV-1 and all 116 eyes of the latently infected rabbits shed virus for at least four consecutive days during induction.

Animals↗
PubMed1983

Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.

The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.

Alleles↗