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E J Browder

Publications and source records attributed to E J Browder.

8 recordsLinked to original sources
PubMed1988

Experimental infection of the nine-banded armadillo (Dasypus novemcinctus) with Schistosoma mansoni (Kenyan strain).

Eleven wild-caught nine-banded armadillos were infected with cercariae of the Kenyan strain of Schistosoma mansoni for 1-25 weeks. Distribution of eggs along and within the gut and liver was similar to that seen in human schistosomiasis. However, egg excretion was poor, eggs were small, rate of infection was low, and the prepatent period was long. From these data it is concluded that Dasypus novemcinctus is an inefficient reservoir host of S. mansoni.

Animals↗
PubMed1984

Characteristics of the phagocytically induced respiratory burst in leukocytes from young adult and aged beagle dogs.

Phagocytically stimulated canine leukocyte suspensions obtained from 12 young adult and 43 aged individuals were examined for several physiological manifestations of the phagocytically induced respiratory burst. There was considerable variation in levels of oxygen consumption, glucose oxidation via the hexose monophosphate shunt (HMPS), and chemiluminescence response by both resting and phagocytically stimulated leukocytes from different individual animals in each age-group. Leukocyte suspensions from specific individuals in each age-group exhibited a weakly responsive respiratory burst. Chronological age could not be used as a predictor of either the specific (oxygen consumption and HMPS activity) or nonspecific (chemiluminescence response) manifestations of the respiratory burst. The kinetics of the chemiluminescence response were similar for all age-groups. Collectively, the results suggest that there is not an age-related alteration in the phagocytically induced respiratory burst of canine neutrophils and that cells from young adult and aged dogs have a comparable capacity to generate levels of highly reactive antimicrobial oxidizing agents. The increased relative susceptibility of aging dogs to microbial agents is apparently not related to an absent, abbreviated, or reduced leukocyte respiratory burst.

Aging↗