Biomedical subjects

E J Díaz-Calavia

Publications and source records attributed to E J Díaz-Calavia.

6 recordsLinked to original sources

PubMed1992

Acute alcoholic intoxication and naloxone. Effects on visual evoked potential.

Experimental assays analyzing visual evoked potential (VEP) changes during an acute alcoholic intoxication were carried out in two groups of cats: One with continuous ethanol (0.06 g/kg.min) i.v. perfusion. Another one with a naloxone (400 micrograms/kg) i.v. injection 10 min before ethylic perfusion. Naloxone potentiates alcohol effects on VEP parameters, and on the appearance of isoelectric postpotential and flat VEP.

Acute Disease↗

PubMed1989

Effect of naloxone on acute ethylic intoxication. An EEG study.

EEG recording has been used to evaluate in cats the effect of naloxone on acute ethylic intoxication (AEI). Naloxone was administered both before and during the course of AEI. Results of the experiment showed that administration of naloxone before the AEI potentiates the toxic effect of alcohol. However, the administration of naloxone in a continuous way along the course of AEI significantly diminished the toxic effect of alcohol.

Animals↗

PubMed1989

Electroencephalographic study of naloxone effects in the recovery of an acute alcoholic intoxication.

Experimental assays analysing EEG changes during the recovery of an acute alcoholic intoxication were carried out in three groups of cats: 1) Recovery of acute alcoholic intoxication produced by continuous intravenous perfusion of ethanol, 0.06 g/kg/min, during 20 minutes. 2) Recovery of acute alcoholic intoxication by injecting naloxone (400 micrograms/kg), just after finishing alcohol perfusion. 3) Recovery of acute alcoholic intoxication by injecting naloxone (400 micrograms/kg), 15 min after finishing perfusion. Naloxone administered after an acute alcoholic intoxication worsens the recovery of EEG parameters; 1-2 (p less than 0.05), 1-3 (p less than 0.05).

Alcoholic Intoxication↗

PubMed1989

[Effects of tobacco smoke applied on various levels of the respiratory tract].

The respiratory and cardiovascular reflex responses of tobacco smoke inhaled through an isolated larynx and directly into the lungs were studied in cats. The inhalation of tobacco smoke directly into the lungs showed the following: tachypnea (p less than 0.01), an increase in inspiratory and expiratory pleural pressure (p less than 0.01, p less than 0.001) with an increase in total lung resistance (p less than 0.01), a decrease in inspiratory and expiratory subglottic pressure (p less than 0.001, p less than 0.02) and an increase in mean arterial pressure (p less than 0.001) with a non significant slight increase of cardiac rate. The inhalation through an isolated larynx showed: bradypnea (p less than 0.01), a non significative decrease in inspiratory and expiratory pleural pressure with no changes in total lung resistance, and an increase in expiratory subglottic pressure (p less than 0.01) with no changes in inspiratory pressure accompanied by several glottic closures. No changes in arterial pressure and cardiac rate were observed. This study shows the existence of two respiratory reflex responses induced by tobacco smoke depending on the respiratory airway level application.

Animals↗

PubMed1989

[Representation of physiologic functions in the modulation domain ].

The axes: amplitude, frequency, time, define a trihedral where the most usual representations occur in time domain (plane defined by the axes amplitude-time). The frequency of an action with respect to time is represented in the plane defined by the axes frequency-time in the so called "Modulation Domain", it is being considered very useful, expressive and easy to construct in the automatic treatment of signals.

Animals↗

PubMed1989

[Experimental conditions which modify the visual evoked potential].

The effect of the visual stimulus intensity on the latency and morphology of the visual evoked potential (VEP) components is studied in cats with chronic implanted electrodes. A lessening in the luminous stimulus intensity is observed to produce a progressive diminution in the amplitude of the initial waves of the VEP till its disappearance, as well as a progressive increase in the latency, following an exponential function. Since the integration in a cortex zone is achieved by pathways of various lengths, the impulses arrive with different delays. It is suggested that stimuli of little intensity generate trains of impulses whose integration, in a small cortex area, is likely characterized by a delay in the appearance of high relative frequencies; whereas high intensity stimuli are more likely to produce high frequencies, in the same cortex area, and with earlier appearance. This may be considered as the explanation for the delay of analogous waves generated by stimuli of lesser intensity.

Animals↗