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Biomedical subjects

E J Donaldson

Publications and source records attributed to E J Donaldson.

8 recordsLinked to original sources
PubMed1992

Iodine-125 irradiation of choroidal melanoma: clinical experience from the Prince of Wales and Sydney Eye Hospitals.

We examined the records of 53 patients treated for choroidal melanoma between 1985 and 1989. The aim of this study was to assess the safety and short-term results of iodine-125 episcleral plaque therapy. There were 28 males and 25 females, aged 20 to 77 years (median 61 years), treated for single tumours with a median diameter of 9 mm (range 5 to 15 mm) and with a median thickness of 4 mm (range 2 to 10 mm). The plaques containing iodine-125 seeds were chosen according to tumour size: 10 mm (16 patients); 15 mm (36 patients); 20 mm (one patient). All patients are alive at last follow-up (median 1.3 years, range 4 months to 3.3 years). Four patients underwent enucleation for melanoma progression. Thirty patients have developed some type of complication (more than one complication occurred in the same eye in 12 patients): retinitis (19), optic neuropathy (7); cataract (4), rubeosis iridis (2). Overall, visual acuity deteriorated in 32 patients, remained stable in 12 patients and improved in 9 patients. Iodine-125 plaque therapy appears to offer patients good prospects of tumour control and preservation of useful vision.

Adult↗
PubMed1983

Angioid streaks.

Angioid streaks were first described by Doyne in 1889. Gronblad proposed in 1929 that they followed disruption of the elastic layer of Bruch's membrane, having noted the association between angioid streaks and pseudoxanthoma elasticum. Several other diseases have been associated with angioid streaks, including Paget's disease and sickle cell disease. Angioid streaks are found predominantly in the 20 to 50 year age-group and may be associated with minimal visual loss, but the problem is the high risk of rapid development of subretinal neovascularisation at the macula with resultant haemorrhage and scarring. Prophylactic light coagulation along the angioid streaks to prevent subretinal neovascularisation is not recommended. However, light coagulation treatment to foci of subretinal neovascularisation is possible if the network is not too close to fixation. As recurrence of neovascularisation is to be expected, very careful follow-up is necessary.

Adolescent↗
PubMed1977

What should we teach? A consensus method to determine curriculum content.

The content of an undergraduate curriculum is usually decided upon by the appropriate University Department. Such a Department is staffed exclusively by specialists in the field. The technique described in this paper is one which uses the perception of a wide variety of doctors, including specialists in the field, other specialists and general practitioners, to determine what should be taught to undergraduate students. The outcome of this study reveals that there is substantial agreement on what basic materials should be taught in an undergraduate curriculum in Ophthalmology. There is a substantial agreement throughout the profession on the basic required competencies in Ophthalmology, but it is clear that general practitioners are much more demanding in their requirements from the undergraduate curriculum than are specialists. Ophthalmologists are the least demanding of the undergraduate. The consensus technique described in this paper is a practical and formative method of obtaining valuable data for use in curriculum construction.

Australia↗