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Biomedical subjects

E J Kerfoot

Publications and source records attributed to E J Kerfoot.

7 recordsLinked to original sources
PubMed1983

Sampling and analytical determination of airborne N,N-dimethylcyclohexylamine.

A method has been developed for the collection on a reactive surface and subsequent analytical determination of airborne N,N-dimethylcyclohexylamine (DMCA). DMCA from ambient or test atmosphere is collected on a Tenax sorbent sample tube treated with hydrochloric acid (HCl) using a low flow, personal sampling pump. The Tenax sorbent sample tube is desorbed with tetrahydrofuran (THF) and sodium hydroxide (NaOH) and the resulting solution is analyzed on a gas chromatograph/mass spectrometer (GC/MS) using selected ion monitor. The peak areas for ions 84 and 127 are integrated and compared to standards. It is shown that collected samples are stable at room temperature for more than 50 days. This method was proven in the laboratory using concentrations in air from 1.0 ppm to 4.1 ppm.

Air↗
PubMed1982

What industrial hygienists should know about TSCA.

Direct participation of industrial hygiene personnel in planning and implementing compliance with several pertinent sections of the Toxic Substances Control Act (TSCA) is warranted. TSCA is administered by the Environmental Protection Agency and there is a variety of areas in which industrial hygiene input is and will be required. Major sections of TSCA which require industrial hygiene participation include Testing, Premanufacture Notices (PMNs), Regulation of Hazardous Chemicals, and Reporting and Recordkeeping. The industrial hygiene input requires interaction with other groups such as Toxicology, Environmental, Government Regulations, Legal, Medical, Research and Development, Marketing and Manufacturing in order to provide a comprehensive response to and compliance with current and anticipated TSCA rules.

Chemical Industry↗
PubMed1981

Occupational health survey: an evaluation of potential health hazards in the workplace.

Critical reviews of production jobs, potential exposure to chemical and physical agents, and job placement policies are necessary to provide a safe and healthful working environment for employees. To achieve this objective, a five-phase survey has been developed at BASF Wyandotte Corporation. Phase one assembles a data bank which cross references chemical substances with job classifications. Phase two provides toxicological evaluation for each chemical, physical, and ergonomic stress. Phase three evaluates the magnitude of each stress for a particular job classification. Phase four identifies present members of the work force or applicants who may have a heightened susceptibility to any stress. Phase five provides an integrated health manual with useful data and materials disseminated to various staff groups, manufacturing personnel, and plant employees.

Chemical Industry↗
PubMed1980

Design of a computerized chemical information file in response to the initial inventory requirements of TSCA.

A computerized file of chemical information, "CHEMFO", was developed at BASF Wyandotte Corporation to help comply with the initial reporting requirements of the Toxic Substances Control Act. This organization and approach allowed collecting the required information on all the manufactured and imported chemicals, editing and entry of the data, structuring of the computer file and interactive capabilities, and selecting the final program and subsequent printout. Besides using this system to meet the TSCA initial inventory reporting requirements, the file also has the capacity to be updated and revised as needed, which further expands its potential benefits. Some of the other information that can be derived from this system are: identification of chemical substances, quantities, and each site; tie-in to the medical/occupational health data bank; foundation for recording the industrial hygiene monitoring data; supplement for toxicology and environmental data base; and index for generating compilation of site specific material on health and environmental information.

Chemical Industry↗
PubMed1975

Cobalt metal inhalation studies on miniature swine.

Cobalt is considered to be the chief component in the tungsten carbide mixture responsible for hard-metal disease. An animal inhalation study was undertaken simulating conditions under which these workers in the tungsten carbide industry are exposed to cobalt. In this semichronic study, miniature swine were exposed to an inhalation of pure cobalt metal powder at concentrations of 0.1% mg/m3 (present TLV) and 1.0 m/m3. At peroidic intervals, the following studies were performed: pulmonary function tests, electrocardiograms, x-ray examinations, blood and urine tests, electron microscopy, and light microscopic pathology. Early detection of pulmonary disease is apparent from the pulmonary function tests showing a mark decrease in lung compliance, and from electron microscopy showing an increase in the amount of septal collagen. This study demonstrates that the present TLV of 0.1 mg/3 for cobalt seems to be too high, even at this relatively brief duration of exposure.

Airway Resistance↗
PubMed1975

Formaldehyde and paraformaldehyde study in funeral homes.

Formaldehyde is a toxic gas and classed as an upper respiratory irritant. The gas possesses distinctive physiological properties causing symptoms familiar to many formaldehyde workers, such as: burning of the eyes, lacrimation, and general irritation of the upper respiratory passages. To demonstrate this toxic action of formaldehyde a study was conducted in embalming rooms of funeral homes to determine the concentration and its effect on the embalmers at this level. The control measures in these establishments were also evaluated and found to be inadequate in some respects. Paraformaldehyde powders were sized and found to contain a respirable fraction. The results of the study show that these workers verified the fact that formaldehyde is an irritant at levels that are below the present Threshold Limit Value.

Air Pollutants, Occupational↗