Monitoring neuromuscular function.
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Biomedical subjects
Publications and source records attributed to E J Monti.
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Many anesthesia practitioners reuse disposable syringes and multidose drug vials from case to case despite the known hazards of blood-borne disease transmission. This practice may be hazardous to both patients and practitioners. Microscopic amounts of blood in the intravenous tubing can cause contamination of syringes, needles, and drug vials. Contaminated multidose vials have been associated with the transmission of both hepatitis B and bacterial infections. This article examines the potential risks of contamination from the reuse of disposable syringes and the myth about the cost savings of this practice.
Oxygen free radicals are byproducts from the fundamental metabolic activities within the body. Normally, radicals are neutralized by enzymatic activity or natural antioxidants. Thus the generation of free radicals poses no problem so long as the balance between oxygen radical production and eradication remains in balance. There are multiple medical conditions, such as myocardial infarction, carcinogenesis, and neurologic trauma, to name a few, that may be aggravated by the presence of oxygen free radicals. This article will present an overview of oxygen free radicals: their normal formation and control and how they might further injure tissue in particular diseases. The implications for health care professionals are highlighted.
This article examines potential mechanisms underlying the neurologic toxicities associated with interferon therapy in patients with cancer. The following mechanisms for interferon-related toxicities have been proposed: changes in certain neuroendocrine hormone levels; structural similarities and common pathways between interferon and specific neuroendocrine hormones; and the immunoregulatory effects of interferon. Strategies for the assessment and management of interferon-related neurologic toxicities are discussed. A reduction in dose or discontinuation of interferon may be recommended if interferon neurotoxicity develops. Additional interventions may include reorientation strategies, provision of uninterrupted periods of rest, and safety precautions. Directions for future research are recommended.