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Biomedical subjects

E J Stewart

Publications and source records attributed to E J Stewart.

20 records · Page 2Linked to original sources
PubMedDate not supplied

Drug switching patterns among patients taking non-steroidal anti-inflammatory drugs: a retrospective cohort study of a general practitioners database in the United Kingdom.

OBJECTIVE: To examine the frequency and determinants of switching between different non-steroidal anti-inflammatory drugs (NSAIDs) and the relationship with co-prescription of gastro-protective drugs (GPDs). DESIGN: This was an analysis of 30,654 patients receiving a total of 209,140 NSAID prescriptions in the UK from 1 January 1997 to 31 December 1998 identified through the MediPlus database. Analyses examined switching, repeat, termination and GPD co-prescription rates in new and continuing takers according to age and sex. RESULTS: Each patient received an average of 6.8 prescriptions in the year of study. Of the prescriptions 72.2% were for one of three NSAIDs, ibuprofen, diclofenac, or naproxen, and 7.2% of prescriptions were for fixed combination products of an NSAID plus a gastroprotective drug. At least 16.0% of continuing takers, and 28.5% of new takers switched to another NSAID in the review period. On average, new patients switched more frequently than continuing patients (0.39 switches/patient/year versus 0.23 switches/patient/year, p < 0.001). Switching between NSAIDs decreased with age and was less common in women (p < 0.05). Switching was associated with a 24% and 33% increased probability of GPD prescription in new and continuing takers, respectively. DISCUSSION: The frequency of switching, and of GPD co-prescription at switching, suggest that dissatisfaction with NSAIDs is frequent, and that gastrointestinal intolerance is a common feature of this dissatisfaction.

Adult↗
PubMedDate not supplied

Preparing children for a surgical experience.

1. Little research has been conducted on the specific fears of children undergoing surgery. One study reported that the events most remembered about the surgical experience were riding to the operating room, receiving injections, waking up in pain, and not being allowed to eat or drink. The most feared events were injections and the anesthesia mask. 2. Many hospitals have developed formal and informal orientation programs for preparing children for surgery. Special orientation days with themes may be offered. Films/videos, slide presentations, coloring books, photograph albums, puppet shows, and tours often are used to introduce the child to the surgical environment. A visit to the operating room may be a part of the program. In some cases, play therapy in a mock operating room is used. 3. A warm, open, honest environment is crucially important. There should be a willingness to discuss the child's ideas, fears, and misconceptions concerning their perioperative experience. In addition, children should be given the opportunity to learn about their body, the health care profession, and the surgical setting.

Adolescent↗