Biomedical subjects

E Jaanio

Publications and source records attributed to E Jaanio.

4 recordsLinked to original sources

PubMed1990

Double-blind group comparative study of 2% nedocromil sodium eye drops with placebo eye drops in the treatment of seasonal allergic conjunctivitis.

A multicenter double-blind group comparative study was carried out in 126 patients, 64 of whom received 2% nedocromil sodium eye drops, and 62 placebo eyedrops twice each day for the treatment of seasonal allergic conjunctivitis to birch pollen. The patients were evaluated at 2 week intervals for clinical signs of conjunctivitis and kept daily diary records of eye symptoms (0-4 severity scales) and concomitant therapy. Diary trends favored active treatment, and reached significance for excessive lacrimation (P less than .05) during peak pollen challenge. Clinic assessments showed the same directional trend and final opinions of treatment efficacy were significantly in favor of nedocromil sodium (P = .003, patients; P = .006, clinicians). In addition, the placebo group used significantly more topical (P less than .05) and oral (P less than .01) concomitant antihistamine therapy. Nedocromil sodium and placebo treatments were equally acceptable and well tolerated. The results show that 2% nedocromil sodium used topically twice each day is an effective therapy for seasonal allergic conjunctivitis.

Anti-Inflammatory Agents, Non-Steroidal↗

PubMed1988

Prevalence of exfoliation syndrome in Finland.

Three separate investigations are reported, covering a total of 795 patients from different parts of Finland, two of them consisting of inmates of old people's homes in two towns (N = 205 and 262) and one a randomly selected population from a rural commune (N = 328). They show the mean prevalence of exfoliation syndrome (PS) to be 14.2% in age group 60 less than or equal to 69 years, 21.9% in age group 70-79 and 34.7% in age group greater than or equal to 80. The prevalence increases statistically significantly with age. The mean prevalence of PS in all three groups was 22.4%. No isolate-like accumulation of PS could be demonstrated. The figures seem representative of the hole country.

Age Factors↗

PubMed1980

Electronic subtraction method for ophthalmic photography.

A commercial electronic subtraction unit originally intended for the study of roentgenograms was used to produce subtraction pictures of fundus fluorescein angiographies. No modifications were needed to make good quality subtraction pictures. The method is fast and inexpensive in contrast to previously described photographic methods. Certain limitations of the present equipment are discussed as well as some possibilities for further development of the apparatus. The method is especially suitable for studies on dynamic processes in the eye and it should prove valuable in the long-term follow-up of chronic diseases such as glaucoma and diabetic retinopathy.

Adult↗

PubMed1980

Demonstration of glaucomatous optic disc changes by electronic subtraction.

We describe a new method, the electronic subtraction, for objective two-dimensional detection, demonstration and recording of glaucomatous optic disc changes. Siemens subtraction unit M 707 A, based on a double videochain and originally developed for the study of roentgenograms, was used. The results show that this technique is useful in demonstrating the progressive damage of neural tissue of the disc and associated alterations in the course of the vessels. Further development of the electronic subtraction method for glaucomatous optic disc evaluation is discussed.

Aged↗