PubMed HealthSearch

Biomedical subjects

E Jakubowska

Publications and source records attributed to E Jakubowska.

8 recordsLinked to original sources

Avoidance acquisition in cats as a function of temporal and intensity factors.

Acquisition of an active bar-pressing avoidance response was investigated in a factorial design with 3, 5 or 9 s CS-US intervals and CSs of 70- or 50-dB of white noise. As the CS-US interval increased the required time to meet the avoidance criterion decreased. The shorter the CS-US interval and the more intense the CS, the shorter the median response latencies observed at the end of the training. The latency data were analyzed in Vincentized fifths of acquisition trials. At the beginning of training, when the highest proportion of responses occurred soon after the US onset, escape latencies were shorter in groups trained with shorter CS-US intervals and the more intense CS. During the 1st and 2nd fifths of training, avoidances occurred with the same probability in each part the CS-US interval. By the middle of the training, after a performance level of 50 percent avoidance responses was reached, a rapid increase in the number of short-latency avoidance was observed, which was more pronounced in groups trained with the 70 dB CS. While the general shape of the latency distributions was preserved during the remaining two fifths of the training, a further increase in the intensity effect was noted, which occurred along with a decrease in the CS-US interval effect. The data are in favour of Two-factor Theory of Avoidance learning and suggest that at various stages of training, different variables emerge for acquisition and consolidation of the avoidance reflex. Data supported the hypothesis that two different mechanisms are involved in performance of short- and long-latency avoidance responses.

Animals

Stimulus intensity effects of acute extinction of the CER in rats.

Two groups of 9 rats were trained in the conditioned emotional response (CER) consisting of suppression of food-motivated behavior as a consequence of the pairing of white noise with unavoidable shock. One group was trained and then extinguished with an 80 dB white noise value and the other with the 50 dB white noise intensity as the conditioned stimulus (CS). The CER acquisition was faster with the more intense CS, however, on the last training day, conditioned suppression reached the same asymptotic level in both groups. Then an acute extinction procedure was introduced, wherein the CS was presented only once a day and lasted continuously until the end of the session with no US presentation during this period. This procedure was repeated over several consecutive days. During the first prolonged CS action, CER extinction was more rapid in the 50- than in 80-dB group. However, on the next extinction day the amount of suppression was less with the more intense CS. The results were discussed in terms of CS intensity effects on learning and performance of the conditioned response.

Acoustic Stimulation

Auditory intensity generalization after CER differentiation training.

Auditory intensity generalization was tested in 32 rats trained in CER (conditioned emotional response) differentiation between the 50- and 70-dB white noise intensities. All generalization gradients showed regular monotonicity across the noise intensity dimension independently on experience with the CS+ value prior to the differentiation training. Two kinds of peak shift were obtained. Stimuli further away from the CS? value and more intense than the CS+ inhibited the on-going food motivated behavior more strongly than the CS+ itself. Stimuli further away from the CS+ value and more intense than the CS? enhanced the on-going behavior more than the CS?. A method of statistical analysis indicated that individual gradients and group data corresponded to the same generalization functions.

Acoustic Stimulation

Differentiation learning as a function of stimulus intensity and previous experience with the CS.

Discrimination between 50- and 70-dB white noise was investigated in rats under three training procedures employing a conditioned emotional response (CER) technique. When a CER was initially established to the CS(+) and then the CS(-) was introduced, clear generalization of the CER from CS(+) to CS(-) was observed at the beginning of differentiation learning. When both CSi were simultaneously introduced from the beginning of training, subjects acquired the CER to both intensities. Only then, did differential response to intensities occur as an effect of CER extinction to the CS(-). Habituation of the white noise intensity used during differentiation learning as the CS(+) exerted only a small effect on the course of training. Under all training procedures differentiation of the 50-dB CS(+) and 70-dB CS(-) was more difficult than between the 70-dB CS(+) and 50-dB CS(-). This finding was related to both slower. acquisition of the CER when the less intense CS was paired with shock and to a marked decrease of suppressive properties of the weak CS(+) together with CER extinction to the more intense CS(-). Even by the end of differentiation learning intensity relations between CSi during criterion sessions exerted a strong effect on the magnitudes of suppression ratios.

Animals