Biomedical subjects

E Jeffrey

Publications and source records attributed to E Jeffrey.

4 recordsLinked to original sources

PubMed2003

Ancilla-assisted quantum process tomography.

Complete and precise characterization of a quantum dynamical process can be achieved via the method of quantum process tomography. Using a source of correlated photons, we have implemented several methods, each investigating a wide range of processes, e.g., unitary, decohering, and polarizing. One of these methods, ancilla-assisted process tomography (AAPT), makes use of an additional "ancilla system," and we have theoretically determined the conditions when AAPT is possible. Surprisingly, entanglement is not required. We present data obtained using both separable and entangled input states. The use of entanglement yields superior results, however.

Journal Article↗

PubMed1996

An extract of soy flour influences serum cholesterol and thyroid hormones in rats and hamsters.

The effects of an ethanol-acetone extract from soy flour on serum lipids and thyroid hormones were studied in rats and hamsters. In Study 1, male Sprague-Dawley rats were fed diets containing protein from ethanol-acetone extracted isolated soy protein (ISP-), nonextracted ISP (ISP), casein (casein-), or casein to which 0.36 mg ethanol-acetone extract/g protein was added (casein+). Rats fed either ISP-containing diet had lower serum total cholesterol concentrations compared with those fed either casein diet (P < 0.05). Lower serum LDL-cholesterol concentrations were present in rats fed either ISP-containing diet and in those fed casein+ compared with those fed casein- (P < 0.05). Adding the extract to casein (casein+) produced higher serum thyroxine concentration and free thyroxine indices compared with all other groups (P < 0.05). In Study 2, male Golden Syrian hamsters were fed experimental diets containing protein from ISP, ISP with added ethanol-acetone extract (0.36 mg extract/g protein; ISP+), casein-, casein+ (0.36 mg extract/g protein), or casein with twice the level of extract (0.72 mg/g protein; casein++). Lower serum total cholesterol and LDL (LDL + VLDL + IDL) cholesterol concentrations were observed in hamsters fed ISP, ISP+ or casein+ compared with those fed casein- (P < 0.05). Addition of the extract at higher levels to casein (casein++) did not lower serum lipids relative to those fed casein-. Serum thyroxine concentration and the free thyroxine index were greater in both ISP groups as well as in hamsters fed casein++ compared with those fed casein- or casein+ (P < 0.05). In conclusion, both studies show that protein from soybeans decreases serum total and LDL cholesterol while the effects on thyroxine are different in rats and hamsters. It is also apparent that the ethanol-acetone extract of soy flour produces changes in serum cholesterol, particularly in the LDL fraction in both species.

Animals↗

PubMed1994

Efficacy of feeding glucosinolate-extracted crambe meal to broiler chicks.

Glucosinolates and their breakdown products (nitriles) have long been implicated as toxic factors when feeding rapeseed (Brassica napus) meals and crambe (Crambe abyssinica) meals to poultry. Accordingly, various methods have been developed to remove these compounds from the meals to enhance their value as feed supplements. Glucosinolates and nitriles were extracted from commercially processed, defatted crambe meal by washing with water or various solvent-water mixtures: 50% isopropanol, 50% acetone, or 50% ethanol. In addition, crambe seed was extruded and extracted in the laboratory with isopropanol or hexane. Water washing of commercially defatted meal proved to be the most effective method of extraction, removing 95% of the glucosinolates and nitriles. Meals were fed to 7-d-old broiler chicks at 10% of the diet for 14 d. Weight gain decreased (P < .05) in most groups; however a greater decrease (P < .01) was observed in birds fed meals with high glucosinolate content. Feed intake also decreased (P < .05) in most groups; consequently, feed efficiencies were similar for all groups. No changes in serum chemistries, triiodothyronine, thyroxine, or tissue lesions were associated with glucosinolate or nitrile intake. A relationship (P < .05, r = .74) was found between weight gain and glucosinolate intake. No correlation was found between feed intake and meal glucosinolate or nitrile concentrations.

Alkenes↗

PubMed1985

The epidemiology of spina bifida in south-western Ohio--1970-1979.

Multiple epidemiological variables of 131 children with spina bifida born during 1970 and 1979 in a seven-county urban/rural region of south-western Ohio were analyzed retrospectively via personal interviews, hospital and clinic records, and birth and stillbirth certificates. The estimated incidence of spina bifida was 0.69/1000. It did not vary over the 10 years, seasonally, or in the urban vs. rural areas. The incidence for whites was three times that for non-whites. Reporting of spina bifida on the birth certificate was found for 52 per cent. Fetal loss in the children's mothers was similar to that for controls. However, there was a high number of therapeutic abortions just prior to the conception of the child with spina bifida. Oral contraceptives were used in the early months of the affected pregnancy more frequently than in controls. Recurrence risk was 3.2 per cent. Almost 12 per cent of the children with spina bifida had other major malformations. Even when the deceased probands were discounted, the malformation rate was higher than in the general population. Siblings of affected children had a less impressive but still increased rate of malformations.

Abnormalities, Multiple↗