[Acute pancreatitis due to lipid-lowering drugs].
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Biomedical subjects
Publications and source records attributed to E Juncadella García.
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OBJECTIVE: To evaluate the aetiological understanding of auricular fibrillation, the control of ventricular frequency and treatment with anticoagulant drugs and plasmatic antiaggregants. DESIGN: Descriptive study. SETTING: The study was carried out in the Just Oliveras Primary Care Centre (Basic Health Area) in L'Hospitalet de Llobregat, Barcelona. PATIENTS AND OTHERS PARTICIPANTS: Between May and December, 1991, the clinical records of 59 patients with auricular fibrillation was checked. MEASUREMENTS AND MAIN RESULTS: The predisposing factors found were as follows: arterial hypertension, 34%; alcohol intake, 23%; valvulopathy, 19%; ischaemic cardiopathy, 14%; and other cardiopathies, 10%. The average ventricular frequency found was 83 beats per minute. The most common drugs used were digitalis and amiodarone, this latter either alone or with other drugs. Out of a total of 21 patients suffering valvulopathy, 9 received treatment with coumarin. Of these 5 presented mitral valvulopathy and 3 a double mitral lesion. Eight patients (13.5%) received acetylsalicylic acid and 4 (6.8%) took other plasmatic antiaggregants. We can conclude that hyperthyroidism has little relevance as a cause of TA x AF. Each patient's possibilities for cardioversion were not assessed in depth. There were an excessive number of patients who had not had antiaggregant/anticoagulant treatment. Finally, we consider that amiodarone, given to control ventricular response, is over-used.
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The patients with acute myocardial infarction raise important problems to the primary health care professionals after hospital discharge. We report six patients covering a wide range of problems related with their control ant therapy: from the asymptomatic infarction discovered during a blood pressure control to patients with cardiac failure, postinfarction angina and arrhythmias. Psychosocial problems are also considered. There is a need to encourage secondary prevention activities in these patients, suppressing and/or controlling the existing risk factors.
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OBJECTIVE: To analyse antibiotic consumption (ABC) and its trend in primary care in an area with a high rate of bacterial resistance during the periods 1993-96 and 2000-02. DESIGN: Comparative, retrospective analysis. SETTING: Costa de Ponent Health Region. Population in 1993-96 period was 1,158,098 inhabitants; in 2000-02 period, 1,188,007 inhabitants. PARTICIPANTS: Those patients in the Area who took AB during the periods under study. MEASUREMENTS: Data obtained from the appropriate records of the Catalan Health Service. Measurement of ABC was the Defined Daily Dose (DDD)/1000 inhabitants/day (DID) [criteria of the WHO Collaborating Centre for Drugs Statistics Methodology]. Trends were quantified as percentage increase or drop, comparing the 1993-96 and 2000-02 periods. The U Mann-Whitney test was used. RESULTS: Overall consumption was high, with a light fall from 17.049 DID during the first period to 15.826 DID in the second (-7.1%). Amoxycillin increased from 4.878 DID (57.6%) to 6.19 DID (67.6%) (+26.8%), but amoxycillin-clavulanic did not rise. The percentages of macrolides, quinolones, cephalosporins, sulphonamides, and tetracyclines were higher in the first period. The variations in the consumption of clarithromycin, azithromycin, cefuroxime, cefixime, and ciprofloxacin between the two periods was the most notable point. CONCLUSIONS: Although overall ABC was high and in accord with the high rate of bacterial resistance in our area, a satisfactory evolutionary trend was found. The fall in consumption in the second period was not significant, but an appropriate modification in its profile was noted: domination of aminopenicillins and drop in macrolides, cephalosporins and fluorquinolones.
This paper, elaborated by consensus between experts from Scientific Societies and the Health Administration, is aimed at providing general guidelines for the elaboration and prompting of cardiovascular disease primary prevention programmes, through individual risk factors screening and control. It is expected to be helpful for primary care professionals. After reviewing the rationale and logistics of the programmes starting in the Spanish context, an outline for the risk screening and assessment of the individuals attending the health services is set out. The strategies for high risk individuals control and the periodic health examination of low risk subjects are developed, emphasizing the multifactorial approach. Lastly operational criteria for the management of each risk factor taking simultaneously into account the whole risk picture, embracing definition criteria and consensus recommendations, are stated.