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Biomedical subjects

E K Sarsebekov

Publications and source records attributed to E K Sarsebekov.

9 recordsLinked to original sources

[Blastomogenic action of heavy vanadium-rich petroleum and its processing products].

The contributors performed a study of the blastomogenic properties of the heavy high vanadium oil processed at different temperatures. Skin applications of the oil and oil products in hybrid mice induced skin tumours in 27.5 (48.7%), pregastric--6.4 (7.6%), genital--15.4 (21.1%) cases. It was established that high temperatures of oil sublimation increased the benzopyrene contents and the oil products' blastomogenic activity.

Animals↗

[Vanadium level in the urine of workers on a shift-work schedule during drilling of oil wells for high-vanadium petroleum].

The study was designed to analyze vanadium content in urine samples of 87 workers engaged in the production of high-vanadium oil and 50 persons of the control group. Statistical data verified an elevated vanadium content in the urine of oil miners and especially of operators of the shop of oil and gas production. Urine concentration of vanadium grew along with the increase in the length of service.

Air Pollutants, Occupational↗

[Benzo(a)pyrene content of grain and the products of its processing].

The content of benz(a)pyrene (BP) was studied in the grain, different sorts of flour and in talkan, a Kazakh national food product, prepared from fried grain. It was found that the grain contained 0.33 micrograms/kg of BP, flour--33-58% of that in the grain. The carcinogen content in flour varied with its kind: the highest BP concentration was detected in rye flour, the lowest--in high-quality wheat flour. In talkan, prepared from fried wheat, the content of BP was twice as much compared to the non-fried wheat, due to the intensity of frying. A man, who makes use of talkan during his life, may receive a significant amount of BP which can be conducive to raising the incidence of tumors of the digestive organs, especially of the esophagus.

Adult↗

[Benzo(a)pyrene content in tea].

Six samples of different kinds and sorts of native tea and 103 samples of tea beverage were tested for the benz(a)pyrene (BP) content. The results of the study showed that the carcinogen content in native tea varied from 2.4 micrograms/kg (in mixed tea No 36) to 3.84 micrograms/kg (in the Georgean tea, sort 1). The BP content in the tea beverage depended on the technology of its production. The carcinogen presence and its content increase in a violated technology of tea production may be an important factor in the genesis of esophagus carcinoma.

Benzo(a)pyrene↗

[The nephrotoxic action of heavy crude with a high vanadium content and of its refinery products].

The samples of vanadium-rich oil obtained from the field in Buzachi peninsula and of this oil products were applied subcutaneously to hybrid mice. In response to the application 27.5-56.6% of the animals developed renal impairment manifest morphologically in the range from acute proliferative glomerulonephritis to nephrosclerosis. Nephrotoxicity of the products increased with elevation of their sublimation temperature. Vanadium concentrations grew respectively. Intraperitoneal introduction of the products to rats provoked acute intracapillary glomerulonephritis with partial tubular and glomerular necrosis associated with acute renal failure.

Animals↗