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Biomedical subjects

E Kargi

Publications and source records attributed to E Kargi.

16 recordsLinked to original sources

Cross-sectional internal diameters of radial, thoracodorsal, and dorsalis pedis arteries in children: relationship to subject sex, age, and body size.

The purpose of this study was to determine the average diameter of the radial, thoracodorsal, and dorsalis pedis arteries in a pediatric population and to evaluate the relationship of these measurements to the subject's age, sex, height, weight, and body mass index (BMI). The internal diameters of the radial, thoracodorsal, and dorsalis pedis arteries were non-invasively studied in 45 normotensive, presumed normal children of various ages (4 to 14 years) with the use of a Doppler system. The average diameters of the radial, thoracodorsal, and dorsalis pedis arteries in females and males were as follows: radial artery 1.39 (SD +/- 0.18) mm and 1.57 (SD +/- 0.18) mm; thoracodorsal artery 1.27 (SD +/- 0.11) mm and 1.36 (SD +/- 0.2) mm; and dorsalis pedis artery 1.22 (SD +/- 0.08) mm and 1.34 (SD +/- 0.12) mm. These were correlated with the age, height, weight, and BMI. Gender had a strong influence on the diameter of these arteries. In a linear regression model, weight was found to be statistically the best independent variable for predicting radial and dorsalis pedis diameters, whereas age was the best predictor for the diameter of the thoracodorsal artery. The diameters of these three arteries in an age group of 4 to 14 years ranged between 1 to 2 mm. The age and weight of the children predicted the diameters of the peripheral arteries.

Adolescent↗

Caffeic acid phenethyl ester improves oxidative organ damage in rat model of thermal trauma.

Severe burn injuries cause functional impairment in distant internal organs. Although this mechanism is not clear, it is possible that free radical toxicity plays an important role. Research in animals and clinical studies have shown that there is a close relationship between a lipid peroxidative reaction and secondary pathological changes following thermal injury. It has been demonstrated that antioxidant treatment prevents oxidative tissue damage associated with thermal trauma. This study was designed to determine the possible protective effect of caffeic acid phenethyl ester (CAPE) treatment against oxidative damage in the kidney and lung induced by thermal injury. Rats were decapitated either 1, 3 or 7 days after burn injury. CAPE was administered intraperitoneally immediately after thermal injury. Kidney and lung tissues were taken for the determination of malondialdehyde (MDA) level, myeloperoxidase (MPO), catalase (CAT), superoxide dismutase (SOD) and xanthine oxidase (XO) activities. Severe skin thermal injury caused a significant decrease in SOD and CAT activities, as well as significant increases in MDA level, XO and MPO activities in tissues during the postburn period. Treatment of rats with CAPE (10 micromol/kg) significantly elevated the decreased SOD and CAT activities, while it decreased MDA levels and MPO as well as XO activity.

Animals↗

Comparison of local anaesthetic effects of tramadol with prilocaine for minor surgical procedures.

BACKGROUND: Recent studies have shown that a local anaesthetic action of tramadol 5% was able to induce a sensory block to pinprick, touch, and cold similar to that of lidocaine 1%. The aim of this study was to compare the local anaesthetic effects of tramadol hydrochloride with prilocaine. METHODS: Sixty ASA I or II patients, undergoing excision of the cutaneous lesions under local anaesthesia, were included in the study. Patients were randomly assigned to receive either 1 ml of tramadol 5% (Group T, n=30) or 1 ml of prilocaine 2% (Group P, n=30) intradermally, in a double-blinded fashion. The degree of the burning sensation and pain at the injection site was documented. Sensory block was assessed 1 min after injection. The patient was asked to report the degree of sensation and to grade touch and pinprick sensation. Two minutes after drug administration, incision was performed and intensity of pain, felt by the patient was evaluated on a four-point scale (0-3). Any local adverse effects were recorded. RESULTS: There was no difference in the quality of block between the two groups. Side effects were noted in both groups with a significant increase in the incidence of local reaction (rash) in Group T (seven patients) when compared with Group P (one patient) (P<0.05). Seven patients in Group T vs four patients in Group P complained of burning at the injection site (P>0.05). CONCLUSIONS: Intradermal tramadol 5% can provide a local anaesthesia similar to the prilocaine but the incidence of local adverse effects is higher.

Adolescent↗

Modified mandibulotomy approach to tumors of the oropharynx.

The surgical approach to tumors in the deep oral cavity, oropharynx, and parapharyngeal space has always been a problem. Midline mandibulotomy for exposure and resection of tumors in these areas is usually essential. However, postoperatively accurate and stable reconstruction of the symphysis is difficult. The authors present a modified notch mandibulotomy in a trapezoidal shape to stabilize the symphysis with only a four-hole miniplate. This shape of the osteotomy reduces the time to return to an unrestricted diet and permits more accurate occlusion.

Adult↗

The use of iliac bone flap as a penile stiffener in a diabetic patient with erectile dysfunction.

A diabetic man with erectile dysfunction in whom two previous attempts at penile prosthesis implantation had failed was treated by using an iliac bone flap as a penile stiffener. The patient had satisfactory sexual function with his penis; it retained its size and stiffness during the 1-year follow-up period. We recommend this method for use in patients in whom multiple earlier attempts at penile prosthesis implantation were unsuccessful.

Adult↗

Penile reconstruction in children using a double vascular pedicle composite groin flap.

The purpose of this report is to describe the use of a double vascular pedicle composite groin flap for penile reconstruction in children. The flap was composed of skin, soft tissue and iliac crest bone. Both deep and superficial circumflex iliac vessels were included in the pedicle to ensure a well-vascularized extended skin and bone in the flap. The procedure was carried out in two stages to allow for the prefabrication of a neourethra which was reconstructed in the flap using a full-thickness skin graft, prior to the transfer of the flap. The large skin island and bone with a dual blood supply enabled reconstruction of the penis of appropriate size and stiffness without vascular compromise. Two boys, aged 8 and 10 years, were treated successfully with this method and followed clinically for 4-12 months.

Arteries↗

Silicone gel sheeting for stabilization of skin grafts.

BACKGROUND: Success of skin grafts depends on sufficient immobilization and early intervention for hematoma, seroma, or infection. OBJECTIVE: To stabilize and cover skin grafts with a tie-over technique using translucent silicone gel sheet. METHODS: Twenty-seven skin defects were resurfaced with skin grafts. A sterile silicone gel sheet was placed over the skin graft. Gel was fixed to the wound edges with skin staplers. RESULTS: All grafts healed without any complication. CONCLUSION: Using silicone gel sheeting on 27 skin grafts, we found that it is an effective method for stabilization and allows direct visualization of the graft in order to inspect hematoma-like complications.

Adolescent↗