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Biomedical subjects

E Kauf

Publications and source records attributed to E Kauf.

At least 37 records · Page 2Linked to original sources
PubMed1991

Influence of intensive exercise on insulin-like growth factor I, thyroid and steroid hormones in female gymnasts.

Long lasting intensive physical exercise leads to growth retardation. Short-limbed girls are selected for the training as gymnasts. In a preliminary study with 9 gymnasts a significant decrease of the IGF-I concentration was found after intensive 3-day exercise. This experiment was repeated with 16 girls (11.7 +/- 0.8 years old). The higher the initial DHEA-S and E2 concentration of the gymnasts, the higher were the IGF-I basal levels. The intensive training resulted in the following changes (basal after exercise): IGF-I: 247 +/- 86-->188 +/- 77 ng/ml, T3: 2.4 +/- 0.4-->2.1 +/- 0.3 nmol/l, T4: 96 +/- 15-->98 +/- 19 nmol/l, DHEA-S: 930 +/- 636-->1018 +/- 701 nmol/l, testosterone: 1.5 +/- 0.3-->1.9 +/- 0.4 nmol/l, cortisol: 824 +/- 272-->799 +/- 219 nmol/l. During the 3-day intensive training, the parallel decrease of IGF-I and T3 concentrations in each sportswomen is particularly impressive. Apart from the sequelae of 'negative' selection, the low T3-syndrome, the anti-insulin effect of high GH secretion and the elevated cortisol concentration are responsible for the growth depression, retardation in bone age and the higher incidence of skeletal problems in these gymnasts with 'exercise-induced' delay in development.

Child↗
PubMed1989

[Multiple endocrine neoplasia of the II B type].

Multiple endocrine neoplasia, type II B (MEN II B) includes thyroid carcinoma, pheochromocytoma, ganglioneuromatosis and marfanoid habitus. Its short-term prognosis is determined by the tumour of the adrenal gland, whereas long-term prognosis is determined by the thyroid carcinoma. Often the well-defined but rare syndrome is diagnosed late. The MEN II B's therapy consists of thyroidectomy and adrenalectomy uni- or bilateral. The 5 year-rate of survival is 75%. Own observations are reported.

Adrenal Gland Neoplasms↗
PubMed1984

Zinc, copper, manganese and gold content of the hair of infants.

In the hair of 41 normal newborn children the amounts of the trace elements zinc, copper, manganese and gold were followed up longitudinally by neutron activation analysis, the samples being taken on the 1st day of life, between the 63th and 109th days, the 200th and 240 th as well as between the 368th and 478th days of life. In the newborn children no correlations among their hair trace elements themselves and with the duration of normal pregnancy, birth weight, weight percentiles according to Lubchenko et al. [21] and birth length were found. The zinc content of 212 +/- 63 ppm, the copper content of 8.1 +/- 2.3 ppm and the manganese content of 0.211 +/- 0.366 ppm agreed well with values in the literature from different parts of the world. The hair gold content was found to be 0.086 +/- 0.006 ppm. In early childhood the trace element contents do not exhibit any dependence on sex. The investigation of trace elements in the hair of babies resulted in the remarkable observation that in the first three months of life zinc, copper and gold contents shows a considerable increase to multiple levels of the birth values, followed by a decrease. This is important for the interpretation of hair trace element analyses in infants. There are significant positive correlations among zinc, copper and gold contents in hair. It must be emphasized that gold, although classified as a non-essential element, behaves in the hair of infants just like the physiologically important essential trace elements zinc and copper.(ABSTRACT TRUNCATED AT 250 WORDS)

Aging↗