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Biomedical subjects

E Kern

Publications and source records attributed to E Kern.

At least 19 recordsLinked to original sources
PubMed1990

A double-blind, placebo-controlled trial of fluoxetine plus behavior modification in the treatment of obese binge-eaters and non-binge-eaters.

To determine whether fluoxetine is effective in the long-term treatment of obesity and whether it is particularly useful in the treatment of obese binge-eaters, the authors randomly assigned 45 obese subjects (22 with binge-eating problems and 23 without binge-eating) to fluoxetine (60 mg/day) or placebo in a 52-week double-blind trial. The 21 subjects who completed the trial made 13 clinic visits and were taught basic behavior modification strategies. Patients treated with fluoxetine plus behavior modification lost significantly more weight than those treated with placebo plus behavior modification. However, the drug did not appear to have a differential benefit for binge-eaters.

Adolescent↗
PubMed1990

[Organ injuries--introduction].

Organ injuries are a frequent occurrence: The Surgical Department of Wuerzburg University treated 270 patients between 1983 and 1987. More than one-fifth of these patients had undergone primary surgery at other hospitals and came to us for reoperation or intensive care. The successful treatment of such severe and often multiple, simultaneous injuries depends on well-trained surgeons whose undelayed consultation with specialists is not impeded by bureaucratic hospital organization.

Abdominal Injuries↗
PubMed1989

["Inoperable" deep rectal cancer].

Rectal carcinoma usually requires surgery. In 1981-1988 43 (8.5%) of 504 patients were considered inoperable for medical, prognostic or technical reasons. Surgery should take the removal of urogenital organs, if necessary, into consideration. Electrosurgery, cryosurgery and laser surgery can be used to reestablish local passage. Twenty-one pelvic exenterations were performed during 52 operations for tumor recurrence. Adjuvant chemotherapy and radiotherapy were applied when needed. Each therapy must be individualized.

Combined Modality Therapy↗
PubMed1989

Encephalopathy and vestibulopathy following short-term hydrocarbon exposure.

Dizziness, headaches, and weakness occurred among three men after short-term hydrocarbon exposure during improper welding procedures in a closed container. Symptoms were related to objective evidence of vestibular and cognitive dysfunction. Symptoms and abnormal test results persisted for 6 to 18 months. Simulation of the accident failed to demonstrate likely exposures except aliphatic hydrocarbons, well within the permissible exposure levels. Short-term exposures to neurotoxins may lead to long-term central nervous system abnormalities.

Accidents↗
PubMed1986

[Combination therapy of obesity with a reducing diet and physical training. Cardiovascular and metabolic effects].

Twenty obese patients were either given a caloric restricted diet (300 kcal/d) over 4 weeks alone or underwent an additional ergometer exercise programme for up to 2 hours daily. Combination therapy resulted in an improvement of physical performance by 26% despite weight loss of 11 kg. Blood pressure could be reduced both at rest and on exercise. Blood pressure regulation and heart rate under orthostatic conditions remained unchanged for both therapeutical approaches. The effect on carbohydrate and lipid metabolism was also more favorable in patients on combination therapy than in those given a reduction diet alone. Combination of reduction diet and physical exercise is therefore superior to caloric restriction alone with regard to cardiovascular and metabolic considerations.

Adult↗