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Biomedical subjects

E Kitai

Publications and source records attributed to E Kitai.

53 records · Page 3Linked to original sources

[Oral contraceptive lowers serum magnesium].

The effect of an oral contraceptive on serum magnesium was assessed in a group of 32 women, mean age 24.2 years, attending a family planning clinic. The pill contained ethinyl estradiol 0.03 mg and levonorgestrel 0.15 mg. As in pregnancy and during estrogen replacement in postmenopausal women, the contraceptive pill lowered serum magnesium (from a mean of 0.82 mmol/l, to 0.61 mmol/l in 6 months). Larger studies may determine whether routine dietary magnesium supplementation is necessary in oral contraception.

Adult↗

[Necrotic pheochromocytoma presenting with shock and abdominal pain].

Pheochromocytoma is a rare tumor, the diagnosis of which is based on a history of hypertension, and symptoms, signs and laboratory data associated with increased release of catecholamines. The combination of pheochromocytoma and shock is uncommon, but when it does occur, is often associated with necrosis of the tumor. We report an unusual case of a patient whose clinical findings suggested fulminating septic shock. Only at postmortem was the diagnosis of pheochromocytoma made.

Abdominal Pain↗

[Smoking behavior of primary-care clinic patients].

Smoking habits in 1027 patients over the age of 18 in our 2 primary care clinics were surveyed by means of questionnaires which were filled out by 92% of the total population surveyed. 31% of the men and 20% of the women smoked, while 22.9% and 9.5%, respectively, were ex-smokers. The proportion of smokers decreased with increasing age. There was a greater proportion of smokers and of heavy smokers in the Tel Mond clinic in which the patients were of Afro-Asian origin and of lower socio-economic status. In the Herut clinic, in which the patients were of European origin and higher socio-economic status, there were fewer smokers and they had started smoking at an older age. 41% of all smokers expressed a desire to stop smoking. 60.7% of those who had stopped smoking had done so because of some illness or symptom. Very few said they had stopped because of medical advice (1.8%) or anti-smoking propaganda in the media (0.6%). Despite the general reduction in smoking since previous studies, there is need for much more intervention by family physicians.

Adult↗

[Physical activity habits of primary care clinic patients].

764 registered clinic patients, between the ages of 18-60, in 2 primary-care clinics, filled out questionnaires about exercise habits. One clinic is in a moshav in which the population is principally of European origin and of high socioeconomic status. The other clinic is in a town in which the population is mainly of North African or Asian origin and of low socioeconomic status. Only 38.6% of those studied defined their work as involving physical or marked physical activity. These tended to be males 18-30 years old living on the moshav. Only 14.2% reported regular sports activity, none of whom were from the town. No differences were noted in sex or age-distribution. Women tended to engage in gymnastics, walking or folk-dancing; men in running or ball sports. Our results are similar to those of other studies which show that Israelis do not tend to engage regularly in sports. It is emphasized that health organizations should encourage sport activity by their members.

Adult↗

[Lowering effect of estrogen replacement treatment on immunoglobulins in menopausal women].

Similarly to the results reported in pregnancy and during oral contraceptive use, estrogen replacement therapy (ERT) had a lowering effect on serum immunoglobulins (IgG, IgA, IgM) of 20 postmenopausal women with a mean age of 52.2 years, in parallel with an increase in the blood values of estradiol (E2). The clinical implications of this phenomenon warrant the study on a bigger series and during a longer period of time. It is recommended to use with precaution the ERT in women with known defects in the immunologic system. A study on the effect of the new transdermal therapeutic system (Estraderm, TTS, Ciba) on the immunoglobulins is in course.

Adult↗

[Use of diuretics in family practice].

Of 1894 patients registered in a family medicine clinic, 101 (5.3%) had been taking diuretics for at least 6 months. The sex distribution was equal and the average age was 68.7 years. 60% were taking Kaluril, 30% Aquadon and 10% Frusemide. Most had hypertension or heart failure, or both. 6 patients developed hyperglycemia, 2 hyponatremia, 5 hypokalemia, 2 hyperkalemia and 10 hyperuricemia. In 19 the ECG showed arrhythmias. 5 of 56 patients had hypomagnesemia and another 12 had low borderline levels. In the light of these results and those in the literature, we conclude that diuretics are not as safe as previously thought.

Aged↗

The link between contraceptive methods and Chlamydia trachomatis infection.

The effect of various contraceptive methods on Chlamydia trachomatis (CT) infection was examined in a group of 158 women, with a mean age of 26.9 years, patients of a family planning clinic. Their symptoms were mild abdominal pain or vaginal discharge. Antibodies to CT were examined by an indirect immunoperoxidase assay, with a commercial kit. From each patient a vaginal smear was collected for bacteriologic and mycologic study. In group I, consisting of 30 married women with a mean age of 31 years, 5 (16.7%) IUD users had a positive test for CT antibodies. In group II, comprising 57 women, with a mean age of 23.3 years, 22 (38.6%) oral contraceptive (OC) users, of whom 94.7% were unmarried, had positive tests for CT antibodies. The difference between these two groups was statistically significant (p less than 0.05). In group III, comprising 71 women with a mean age of 28.1 years, 62% unmarried and using other contraceptive methods, 15 (21.1%) had a positive test for CT antibodies. The incidence of CT infection was not different in the 3 groups under study, when the factors of age and marital status were taken into consideration (p greater than 0.30). Bacterial vaginal infection was found in 43.3% of the IUD users, compared with only 14% of the OC users (p less than 0.01). In contrast, in the OC users, candidiasis was predominant, the difference from the other groups being statistically significant (p less than 0.001). The women with positive antibodies also more frequently had colonies of bacterial and mycological vaginal infection.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Sexual behaviour, a stress factor affecting ovulation and cycle length.

The hormonal profile and clinical picture of women, mean age 21 years, with aberrant anovulatory cycles, lasting from 35-65 days were presented. Although all subjects had orgasmic experiences by automanipulation, and 4 had sporadic sex with men, the fact of not having regular heterosexual relationship, acts as an emotional stress, with resulting higher PRL and urinary catecholamine level, as compared to an age-matched control group of 14 women, having regular 1-2 weekly coitus. Sexual behaviour affects cycle length and ovulation, having no effect on estradiol level. Menstrual disorders and aberrant long cycles, resulting from absence of or sporadic sexual encounters should not be treated. They are a temporary phenomenon, which disappears after establishment of normal heterosexual life-style.

Adolescent↗

An epidemiological study of lateral epicondylitis (tennis elbow) in amateur male players.

Our epidemiological study investigated lateral epicondylitis (tennis elbow) among 150 nonprofessional male tennis players (75% of the players approached consecutively) interviewed and examined physically at four local tennis clubs. The interview and examination covered over sixty possible risk factors, including demographic data, playing habits, anatomical measurements and racket characteristics. The "average" painfree player is 38 years old, has played tennis 11 years, and plays 5.5 hours a week, usually with a racket whose head area is 570 cm2. The "average" tennis elbow sufferer is a 45-year-old player who has been playing 16 years and has played 8 hours weekly before onset of pain with a racket whose head area is 613 cm2. Multivariate analysis indicated that number of playing years has no independent effect beyond its association with age. Playing hours per week, current age and age at pain onset have independent significant effects on number of pain episodes (0-7). Weekly number of playing hours is the best predictor of pain category (none, one or more currently or in the past).

Adult↗

Attitudes of Israeli family physicians toward clinical guidelines.

BACKGROUND: Many clinical guidelines (CGs) have been written during the past few years. Although family physicians (FPs) stand to benefit from many of these CGs, incorporating new CGs into daily practice seems to present a challenge. OBJECTIVE: To evaluate Israeli FPs' attitudes toward CGs. METHODS: We administered an anonymous questionnaire to general practitioners, residents, and board-certified FPs who participated in continuing medical education programs throughout Israel during May and June 1998. Our survey focused on physician attitudes and behaviors regarding CGs in general, and to CGs for treating the patient with diabetes mellitus (DM) in particular. The CGs for patients with DM have recently been promoted in the context of primary care quality improvement programs. Respondents also provided demographic and professional data. RESULTS: Of the 404 questionnaires distributed, 293 questionnaires were returned for a response rate of 83%. The average (+/-SD) age of respondents was 40.2 +/- 7.0 years, with a mean (+/-SD) of 13.3 +/- 8.0 years in practice. Overall, opinion regarding CGs was positive. About half of the respondents thought CGs improved patient compliance. Comparisons between the various physician groups highlighted several notable differences. Two thirds of the general practitioners believed CGs improved patient compliance, while this was true of only one third of the FPs (P<.001). Most FPs (62%) and senior residents (69%) felt CGs did not constrain their clinical freedom, while less than half of the general practitioners and junior residents felt this way (P =.045). Eighty-three percent of all respondents agreed that the CGs for the treatment of DM were able to be implemented, and 75% believed the CGs assisted them in the management of patients with DM. Whereas 39% expressed concern about being able to adapt generic CGs to individual patient needs, only 27% (P =.002) felt this way about the DM CGs. The vast majority (92%) were interested in understanding the scientific evidence supporting CGs as a prerequisite to adopting them. Most respondents preferred limiting CG length to a maximum of 5 pages. CONCLUSIONS: We found support among Israeli FPs for the use of CGs. Clinical guidelines seem to be used in the field, in particular those developed for treating DM. In light of our findings, attention should be focused on optimally tailoring new CGs to meet scientific standards and crafting them to suit the preferences of local FPs.

Adult↗