PubMed Health⌕ Search

Biomedical subjects

E Kleriga

Publications and source records attributed to E Kleriga.

7 recordsLinked to original sources
PubMed1984

Complications associated with intra-arterial BCNU administered in combination with vincristine and procarbazine for the treatment of malignant brain tumors.

We have used intra-arterial (i.a.) 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) either alone or as part of adjuvant chemotherapy in patients with malignant brain tumors over a 3 year period (1979-1982). The i.a. BCNU technique was used 111 times to infuse 134 arteries in 37 patients. These patients, 28 cases with glial tumor and 9 cases with brain metastasis, received i.a. BCNU in combination with Vincristine and Procarbazine every 6 weeks. Complications encountered were transient and included: periorbital erythralgia or occipital-nuchal pain in 23 (62%), mild confusion and disorientation in 14 (38%), and ipsilateral conjunctival edema in 10 (27%). Reversible myelosuppression was not found. Our findings suggest that BCNU (100 mg/M2) may be given by i.a. infusion in combination chemotherapy without persistent severe untoward effects with a cumulative dose of 700 mg/M2.

Adolescent↗
PubMed1983

Mechanisms of hydrocephalus in cerebral cysticercosis: implications for therapy.

Patients with hydrocephalus secondary to cerebral cysticercosis are a highly heterogeneous group. The mechanisms of hydrocephalus in these patients are multiple. Intraventricular cysts may be found in the 3rd and 4th ventricles, the sylvian aqueduct, and the foramen of Monro. Intraventricular cysts can be suspected when the 3rd and 4th ventricles or aqueduct remain enlarged despite shunting. Intraventricular contrast medium demonstrates the presence of the parasites. The intraventricular cysts should be removed surgically. Hydrocephalus due to cisternal cysticercosis can be diagnosed by isotope cisternography. These patients should receive shunts, but the long term prognosis is probably poor. Guidelines for the management of hydrocephalus due to cysticercosis are suggested.

Adult↗
PubMed1980

Microsurgical anatomy of the pineal region.

The microsurgical anatomy of the pineal region was studied in 30 cadaver brains after the injection of a colored barium/gelatin mixture into the basilar artery and the straight sinus. The relationships of the pineal gland, vein of Galen, precentral cerebellar vein, internal cerebral veins, basal veins of Rosenthal, medial posterior choroidal arteries, quadrigeminal plate, pulvinar, splenium of the corpus callosum, and posterior 3rd ventricle were examined with the operating microscope and are described.

Cerebellum↗
PubMed1980

Fourth ventricular cysticercosis.

This is a review of the clinical presentation and results of surgical treatment of 25 cases of cysticercosis of the 4th ventricle. All of the patients presented with hydrocephalus and, after shunting, dilatation of the 4th ventricle persisted while the supratentorial ventricular system returned to its normal size. We propose that, after a shunt procedure is performed, early direct surgical excision of the parasite should be done. Good or excellent results were achieved in 81.4% of the patients. Associated arachnoiditis and vasculitis were the major causes of poor outcomes.

Adult↗