PubMed Health⌕ Search

Biomedical subjects

E Klinger

Publications and source records attributed to E Klinger.

31 records · Page 2Linked to original sources
PubMed1984

Cumulative effects of age and pathology on plasma carcinoembryonic antigen in an unselected elderly population.

Plasma CEA was measured in 776 institutionalized elderly patients, 593 women and 183 men, whose mean age was 80.8 +/- 9.7 yr. Of these subjects 39 were found to be free of any pathology and were considered as a control group. All the other subjects had a variety of diseases, malignant or not, known or not known to be associated with elevated CEA. This study showed that elderly people in their 80s, in apparent good health, had higher levels of CEA (3.0 +/- 1.4 ng/ml) than younger people. These levels were shown to be significantly increased in a large number of non-malignant diseases. No correlation could be found between elevated CEA values and autopsy finding or drug administration. Using the chi square test, the number of patients with CEA levels greater than 5 ng/ml was found to be significantly higher in chronic renal failure and cancer. Mortality was also found to be higher in patients with CEA levels greater than 5 ng/ml during a 25-month follow-up. Higher levels of CEA in elderly subjects in apparent good health, as well as increase of these levels in a large set of non-malignant pathology, must thus be kept in mind when interpreting data arising from old people because of both the false-positive (healthy elderly subjects) and the cumulative effects of polypathology on plasma CEA.

Aged↗
PubMed1984

A consciousness-sampling analysis of test anxiety and performance.

In order to evaluate cognitive-interference, reassertion, and reaction-to-performance models of test anxiety, 82 students completed the Test Anxiety Scale, provided state measures of anxiety just before and after a course examination, described their preparation for the test, and reported thought content and state anxiety up to six times during the test. Test Anxiety Scale scores were predictive of pre- and posttest state anxiety but not performance or problem-solving thought frequency during the test. Thought content was significantly but weakly correlated with performance, which was well correlated with posttest state anxiety but not with pretest anxiety. Pretest state anxiety was virtually uncorrelated with posttest state anxiety, with the correlations gradually declining during the test. Question-answering thought content correlated inversely with anxiety during the test. There was no group for whom anxiety appeared to facilitate performance. Preparation correlated only with performance. The pattern of results appears inconsistent with a cognitive-interference interpretation of test anxiety and suggests that in the naturalistic setting used, anxiety is more clearly an effect than a cause of poor performance.

Achievement↗
PubMed1984

[Renal clearance technic for individualizing lithium dosage in routine hospital care].

Lithium has a narrow therapeutic index and exhibits a wide pharmacokinetic variability. Individual dosage regimen adjustment is necessary to warrant the efficacy and safety of long-term treatment. We propose the "renal clearance method" for rapid determination of the lithium carbonate daily dose for chronic therapy. After the first intake of drug by a manic-depressive patient, a four-hour trial is performed. It involves two blood samplings and two urine collections, in which lithium and creatine are assayed. Comparison of observed creatinine with a value predicted according to age, morphological characteristics, sex and serum creatinine of the patients allows the interpretation of conflicting results. The estimation of lithium and creatinine clearances of each patient is performed using a computerized or manual method which unfolds a decision procedure. The daily dosage (1.5 to 6 250 mg tablets in two or three daily intakes) is deduced from the according lithium renal clearance (0.4 to over 2 l/h) by means of a nomogram established in previous studies on about 50 patients. The clearance method has been investigated in routine hospital care on a 40 patients sample. The range of satisfactory lithium serum levels during patients monitoring was 0.6-0.9 mmol/l. Accurate dosage regimen forecasting is obtained in 92% of the patients. The percentage observed in a subset of 13 patients with the C24 method, which relies on a unique blood sample 24 hours after the first dose, was much lower (54%). The renal clearance method appears as a robust and reliable technique for individual lithium dosage regimen adjustment in routine care.

Adult↗
PubMed1983

Discriminability of regular, light, and alcoholic and nonalcoholic near beer.

The usability of near beer as a carrier beverage for research that varies alcoholic content is supported because, in a beer-sampling experiment, light beer was not significantly discriminated from regular beer, and near beer without ethanol was not significantly discriminated from near beer with 3.2% ethanol.

Adult↗
PubMed1976

Self states and performances of preadolescent boys carrying out leadership roles inconsistent with their social status.

A sample of 221 Boy Scouts was formed into (usually) 4-man teams which competed in 3 games of skill. 1 member of each team was randomly designated as its captain, with powers to administer and reward. All subjects took modified Thematic Apperception Tests (TATs) and adjective checklists. Captains who were already leaders in their troops responded with decreased élan. Captains who were not leaders responded with decreased élan and, in some cases, with feeling of withdrawal from relating to others and ineffectiveness as captains. The effects were unrelated to the actual success of their teams.

Adolescent↗
PubMedDate not supplied

Temptation, restriction, and alcohol consumption among American and German college students.

To assess relationships between alcohol consumption and two dimensions of drinking restraint (temptation and restriction), American and German college students were given the Khavari Alcohol Test (KAT) and the Temptation and Restraint Inventory (TRI). As hypothesized, drinking temptation was a positive predictor of students' alcohol consumption in both countries, but there was no main effect for drinking restriction. Also as hypothesized, American students who were high on drinking temptation drank greater (not smaller) quantities of alcohol if they were also high on drinking restriction. Conversely, German students who were high on drinking temptation drank more alcohol if they were also low on drinking restriction. The results point to cross-cultural similarities and differences in relationships between drinking temptation and restriction and actual alcohol consumption.

Adolescent↗