PubMed Health⌕ Search

Biomedical subjects

E Kmety

Publications and source records attributed to E Kmety.

47 records · Page 3Linked to original sources
PubMed1972

Research needs in leptospirosis.

Leptospirosis is a widespread infection of man and animals, and locally it assumes considerable importance as a public health and economic problem. It is an important occupational infection among persons working with animals or in environments that may be contaminated by infected animals. In recent years, considerable attention has been devoted to this infection but efforts to control and eliminate it, especially from natural foci, are hindered by gaps in our knowledge. This memorandum is a review of recent progress and current problems in leptospirosis research, with special reference to taxonomy, epidemiological methods, and control measures. Certain aspects of the basic biology of leptospires that are relevant to these topics are also discussed.

Agglutination↗
PubMed1970

Further standardization of the agglutinin-absorption test in the serology of leptospires.

Four factors, suspected of influencing the final results of agglutinin-absorption tests used in the diagnosis and classification of leptospires, were investigated in comparative studies: (1) the time required for adequate absorption, (2) the quantitative relationship between antibody titres and amounts of antigen needed for absorption, (3) the possible effect of the Danysz phenomenon, and (4) the absorptive potency of live and formol-treated antigen.It was found that a 90-minute absorption time was adequate and that with increasing amounts of antigen, titres were continuously reduced, indicating a certain degree of non-specific absorption. The Danysz phenomenon was found to occur in leptospiral serology and the addition of antigen to serum in 3 equal parts at 10-minute intervals is recommended.The titres of sera absorbed with formol-treated antigen were often found to be lower than titres of sera absorbed with the same amounts of live antigen and some damaging effect of formol on antibody is suspected.

Absorption↗