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Biomedical subjects

E Koff

Publications and source records attributed to E Koff.

At least 37 records · Page 2Linked to original sources

Premenarcheal predictors of the experience of menarche: a prospective study.

The goals of this study were (1) to assess, with a prospective design, the impact of premenarcheal menstrual attitudes and personality attributes for menarcheal experience and (2) to assess the relative strength of these variables, in relation to menarcheal timing and preparation for menarche, for predicting menarcheal experience. The subjects were 92 girls, who changed from pre- to postmenarcheal between two test occasions, 6 months apart. When premenarcheal menstrual attitudes and personality attributes were examined independently, results revealed that affirmation, a menstrual attitude, and depression significantly predicted emotional response to menarche. When these two variables were examined, together with preparation and timing variables, the two significant predictors of menarcheal experience were preparation and affirmation. The results provide direction for, and optimism about, the potential efficacy of menstrual education in promoting more positive menarcheal experience.

Adolescent↗

Perceiver and poser asymmetries in processing facial emotion.

This study examined both perceiver and poser asymmetries in processing facial emotion. Posers were left brain-damaged (LBD), right brain-damaged (RBD), and normal control (NC) right-handed males videotaped while expressing happiness and anger. Perceivers rated the facial expressions for asymmetry in original and reversed orientations. Overall, expressions viewed in the reversed orientation were rated as more left-sided than in the original orientation. In the reversed orientation, the more extensive left hemiface of the NCs and LBDs fell in the perceiver's left hemispace. This finding is consistent with previous research demonstrating a left hemispace bias for free-field viewing of emotional faces. Expressions were produced significantly more intensely on the left than the right hemiface by NCs and LBDs; expressions of RBDs were not significantly lateralized.

Adult↗

Conceptions and misconceptions of the menstrual cycle.

Eighty college women were queried about their knowledge of three aspects of the menstrual cycle (menstruation, ovulation, and menopause). Questions concerned the biology of each event and the physical, emotional, and cognitive changes believed to be associated with them. Reasoning from the biases and limitations in the scientific and popular literature, it was predicted that: (1) women would be relatively uninformed about the menstrual cycle, but more informed about menstruation than about ovulation or menopause, and (2) negatively valued changes would be described more frequently than positively valued ones. Results indicated that basic knowledge of the menstrual cycle, even among well-educated women, is at times incorrect, generally incomplete, and negatively biased. These findings confirm the need for a more comprehensive approach to menstrual education that speaks both to the biology of the menstrual cycle and to norms and variability of associated physical and behavioral changes.

Adult↗

A preliminary characterization of lexical emotional expression in right and left brain-damaged patients.

Disorders in nonverbal communication of emotion have been documented in patients with right hemisphere pathology; lexical expression of emotion is virtually unstudied. In this preliminary investigation, emotionally laden slides were used to elicit discourse from right brain-damaged (RBD), left brain-damaged (LBD), and normal control (NC) subjects. New techniques were developed to examine the ability of these subjects to express emotion in words; formalistic and pragmatic analyses of the discourse were conducted. RBDs, relative to NCs and LBDs, were less successful in using words to convey emotion and produced words of lower emotional intensity. LBD aphasics, despite their linguistic deficits, were comparable to NCs in conveying emotional valence. The data tend to support the speculation that the right hemisphere is dominant for lexical expression of emotion. This study has implications for the neuropsychological investigation of language, emotion, and the brain.

Brain Damage, Chronic↗

Facial asymmetry while posing positive and negative emotions: support for the right hemisphere hypothesis.

The purpose of this report was to examine facial asymmetry during the expression of positive and negative emotions. In addition, methodological factors in the study of facial asymmetry were considered. Subjects were 16 neurologically-healthy right-handed adult males, videotaped while posing eight facial expressions (positive and negative) under two conditions (verbal command and visual imitation). Separate asymmetry ratings of the two sides of the face were made by judges viewing normal or mirror-reversed versions of the videotape. There were no effects of valence, condition, or videotape orientation on the asymmetry ratings, and, in general, expressions were produced significantly more intensely on the left than the right side of the face. This finding is consistent with the hypothesis that the right cerebral hemisphere is dominant for the expression of facial emotion of both valences.

Dominance, Cerebral↗

Emotional and non-emotional facial behaviour in patients with unilateral brain damage.

Aspects of emotional facial expression (responsivity, appropriateness, intensity) were examined in brain-damaged adults with right or left hemisphere cerebrovascular lesions and in normal controls. Subjects were videotaped during experimental procedures designed to elicit emotional facial expression and non-emotional facial movement (paralysis, mobility, praxis). On tasks of emotional facial expression, patients with right hemisphere pathology were less responsive and less appropriate than patients with left hemisphere pathology or normal controls. These results corroborate other research findings that the right cerebral hemisphere is dominant for the expression of facial emotion. Both brain-damaged groups had substantial facial paralysis and impairment in muscular mobility on the hemiface contralateral to site of lesion, and the left brain-damaged group had bucco-facial apraxia. Performance measures of emotional expression and non-emotional movement were uncorrelated, suggesting a dissociation between these two systems of facial behaviour.

Apraxias↗

Posed facial emotional expression in brain-damaged patients.

Posed emotional facial expression was examined in brain-damaged adults with right (RBD) or left (LBD) hemisphere cerebrovascular lesions and in matched normal controls (NC). Subjects were videotaped while posing eight facial expressions (positive and negative) under two elicitation conditions (verbal command and visual imitation). Expressions were rated by four naïve judges for intensity, category accuracy, and valence accuracy. RBDs were significantly more impaired than LBDs or NCs on category and valence accuracy, while LBDs posed expressions with significantly more intensity than RBDs or NCs. These findings held for positive emotions only. The results for category accuracy replicate an earlier report (Borod et al., 1986) which utilized a different rating procedure. Finally, expressions posed to visual imitation were rated as more intense and more accurate than those posed to verbal command.

Brain Damage, Chronic↗

Flashbulb memories of menarche and adult menstrual distress.

Ninety-nine female college students completed a questionnaire in which they recounted their memories of menarche, described menarcheal circumstances, and completed the Menstrual Distress Questionnaire (MDQ). Consistent with previous research, inadequate emotional preparation for menstruation was associated with negative feelings at menarche. However, menarcheal circumstances were not strongly predictive of adult MDQ scores. Consistent with memory theory, the amount of information in memories of menarche was negatively related to adequacy of prior knowledge about menstruation: Women who reported feeling less knowledgeable at menarche provided more information about the first episode. While memories of menarche contain information that is relevant to subsequent menstrual experiences, the relationship between menarcheal events and adult menstrual distress appears to be minor.

Adaptation, Psychological↗

Effect of emotional context on bucco-facial apraxia.

Patients with left- and right-hemisphere cerebrovascular pathology and normal adult controls were videotaped while executing tasks of bucco-facial praxis in emotional and nonemotional conditions. Each practic movement was assessed for accuracy and motor execution. Left-brain-damaged patients were significantly impaired on these tasks relative to right-damaged patients and controls. When emotional context was provided, apractic performance improved significantly.

Apraxias↗

Computed tomographic scan hemispheric asymmetries in right- and left-handed male and female subjects.

Patterns of computed tomographic scan asymmetries in the frontal and occipital regions of the brain were examined in 172 right- and left-handed male and female subjects; these patterns were compared with those published previously to determine which asymmetries were reliable across studies. The patterns observed appeared to be unrelated to handedness or sex and suggested that, especially in the posterior region of the brain, the majority of individuals have left hemispheres longer and wider than their right hemispheres. If anatomic asymmetries are indeed substrates for functional asymmetries, it appears more likely that they are related to at least some aspects of language dominance than to cerebral dominance for handedness.

Adolescent↗

The expression and perception of facial emotion in brain-damaged patients.

This study examined the expression and perception of facial emotion in patients with unilateral cerebrovascular pathology. Subjects were 12 right brain-damaged (RBD), 15 left brain-damaged (LBD) aphasic, and 16 normal control (NC) right-handed males. Expressions were elicited during posed and spontaneous conditions. Both positive and negative emotions were studied. RBDs were significantly impaired, relative to LBDs and NCs, in expressing and perceiving facial emotion. There were no group differences as a function of condition, but there were differences as a function of emotional valence. Qualitative performance differences also were observed. There was no evidence that the ability to produce a particular emotion was related to the ability to identify the same emotion. Overall, these findings support the notion that the right cerebral hemisphere is dominant for expressing and perceiving facial emotion.

Adult↗

Channels of emotional expression in patients with unilateral brain damage.

The contribution of facial, intonational, and speech channels to spontaneous emotional expression was examined in right brain-damaged (RBD), left brain-damaged (LBD), and normal control (NC) subjects. Subjects were videotaped while viewing and responding to a series of emotionally laden slides; the videotapes were then rated for the three channels of communication. Overall, RBDs used facial expression and intonation less frequently than the other two groups. When the speech output channel was analyzed, oral expression of feelings in the RBDs, relative to the LBDs and NCs, was less appropriate, more propositional than prosodic, and more descriptive than affective. When the ratings for the three channels of communication were examined, facial expression and intonation were significantly correlated for all subjects.

Affect↗

Development of hemiface size asymmetry.

Facial size asymmetries for the upper and lower face were measured from photographs of 40 neonates (3 days old), 40 preschoolers (2-4 years), and 40 young adults (18-24 years), approximately equally divided by sex. The right hemiface was significantly larger than the left in the three age groups, and there were no differences in the distributions of asymmetry as a function of age.

Adolescent↗

Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes.

The prevalence (lifetime occurrence) rate of cancers of the reproductive system (uterus, ovary, cervix and vagina) and breast cancer was determined for 5,398 living alumnae, 2,622 of whom were former college athletes and 2,776 non-athletes, from data on medical and reproductive history, athletic training and diet. The former athletes had a significantly lower risk of cancer of the breast and reproductive system than did the non-athletes. The relative risk (RR), non-athletes/athletes, for cancers of the reproductive system was 2.53. 95% confidence limits (CL) (1.17, 5.47). The RR for breast cancer was 1.86, 95% CL (1.00, 3.47). The analysis controlled for potential confounding factors including age, family history of cancer, age of menarche, number of pregnancies, use of oral contraceptives, use of oestrogen in the menopausal period, smoking, and leanness. Of the college athletes, 82.4% had been on pre-college teams compared to 24.9% of the college non-athletes. We conclude that long term athletic training may lower the risk of breast cancer and cancers of the reproductive system.

Adult↗

Left-handers and right-handers compared on performance and preference measures of lateral dominance.

Ninety-three right-handed and 53 left-handed adults were compared on a range of performance and preference measures of handedness and footedness. Performance measures included tests of accuracy, speed, and strength. Non-parametric statistical procedures were used to determine whether left-handers (LHs) were less lateralized than right-handers (RHs), and whether distributions for LHs were the mirror images of those for RHs. On performance measures, the distributions for LHs and RHs were generally normal and similar in central tendency, shape, and range. However, on preference measures, distributions were J-shaped, and LHs were significantly less lateralized and more widely dispersed than RHs. Correlations among performance measures were generally low for all subjects. Sex and familial left-handedness did not significantly moderate the responses of these right- and left-handers on performance or preference measures of lateral dominance.

Adult↗