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Biomedical subjects

E Kownacki

Publications and source records attributed to E Kownacki.

3 recordsLinked to original sources

[Magnesium sulfate 4% xylitol infusions solution for the treatment of hypertensive disorders in pregnancy].

A new magnesium sulphate solution with xylitol for the management of hypertensive disorders during pregnancy has been described. The solution contains 40 g MgSO4 and 16 g xylit in 1000 ml and is isoosmotic with blood serum. It can be sterilised for 15 min. at 121 degrees C without risk of decomposition of the ingredients during and after autoclaving. The solution has been proved in the clinical practice.

Female↗

[Polyelectrolyte solution for pediatric PN/TPN mixtures].

Pediatric patients who receive parenteral nutrition (PN) or total parenteral nutrition (TPN) have very high calcium and phosphorus requirements for bone mineralisation. Providing sufficient quantities of these electrolytes is difficult because of calcium and phosphorus solubility limitations in PN-/TPN-mixtures. The preparation and the analytical procedure of the special polyelectrolyte solution containing: 30 mmol Ca2+, 30 mmol P, and 20 mmol Mg2+ pro litre is described. The solution is compatible with fat emulsions and other ingredients of all-in-one-solutions.

Child, Preschool↗

[Sterilization of non-air evacuated infusion flasks containing little water].

Studies have been carried out in connection with the sterilization of glass infusion bottles from which air had not been evacuated and containing certain limited quantities of water. Bottles with a capacity of 500 and 1000 cm3 were filled with 1-3 cm3 distilled water and sterilized in an autoclave for 20 min. set at a temperature of 121 degrees C reaching up to 126 degrees C. The sterility was tested by introducing bags containing Bacillus stearothermophilus spores into the centre of the bottles. Following sterilization the bottles were examined for the growth of spores allowing an incubation period of 7 days at 37 degrees C. Based on the actual conditions of this investigation, it would appear that a bottle from which air has not been evacuated should contain at least 2% (V/V) distilled water, when sterilized in an autoclave. It is, however, strongly recommended that the present findings should be validated based on actual conditions prevailing for individual sterilization procedures.

Drug Packaging↗