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Biomedical subjects

E Kusaba

Publications and source records attributed to E Kusaba.

At least 19 recordsLinked to original sources

[Aortic aneurysm complicated with coarctation of the aorta and Turner syndrome].

A 23-year-old female with Turner syndrome and horse-shoe kidney underwent the operation of the coarctation of the aorta associated with the thoracic aortic aneurysm. The aortic aneurysm was located between the left carotid artery and the coarctation of the aorta, and the subclavian artery which was branched away from the aortic aneurysm was also aneurysmal. Aneurysmectomies and the reconstruction of the descending thoracic aorta and the left subclavian artery were performed with knitted Dacron grafts under assisting of the left atriodescending thoracic aortic bypass with Bio-pump. The disease was rare and such a case was not reported previously.

Adult↗

[Surgical treatment of patent ductus arteriosus in extremely premature infants].

During the last 9 years, 25 extremely premature infants (less than 1,000 g, mean gestational ages of 26.6 weeks, mean birth weight of 838 g) underwent ligation of PDA in operating room. There were no deaths related to surgery. Nineteen (76%) of these infants with RDS were discharged from the hospital, but five died of sepsis, and one died with poor nutrition. In nineteen survivors, 12 infants (63%) with gestational ages under 28 weeks had complicated bronchopulmonary dysplasia (BPD) but all developed normally with good nutrition due to sufficient lactation and fluid therapy after PDA ligation. Results indicate that PDA ligation in extremely premature infants is a safe and effective procedure, because it will prevent the development of BPD and give these infants body weight gain with good nutrition.

Ductus Arteriosus, Patent↗

[Hepatic artery reconstruction grafting with the right gastroepiploic artery for surgical treatment of upper bile duct cancer].

The right gastroepiploic artery (GEA) was used as hepatic artery graft in 2 patients with advanced upper bile duct cancer. The pedicle, including the right GEA and surrounding tissues, was mobilized along greater curvature of the stomach. The GEA pedicle was raised up beyond the gastric pylorus and was anastomosed to the distal right hepatic artery by interrupted suture technique using 7-0 monofilament-nylon stitches. The patients recovered well without evidences of anastomotic dehiscence of hepatico-jejunostomy and prolonged liver dysfunction beyond three postoperative days. Angiograms at one week after operation showed good patency of the GEA graft. The method of hepatic artery grafting with the right GEA is very simple and useful for surgical treatment of upper bile duct cancer.

Aged↗

[A new technique to prepare non-reversed autovein graft].

Non-reversed autovein graft was prepared by using a long saphenous vein. Disposable enema-syringe was used for vein graft to be turned inside out easily, and venous valves were resected out completely. After these procedure, a graft was put with syringe again, and turned outside in with same maneurver. Then, a non-reversed autovein graft without valves was prepared. We believe this is an excellent method to prepare non-reversed valveless autovein graft to be used as bypass grafting for cardiovascular surgery.

Humans↗

Myonephropathic-metabolic syndrome as a complication of cardiopulmonary bypass.

We encountered eight rare cases of myonephropathic metabolic syndrome (MNMS) which developed as a complication of the femoral arterial cannulation (FAC) during cardiopulmonary bypass (CPB). Seven were boys ranging in age from 4-17 years, and all had undergone open heart surgery using CPB with a hemodilution technique. These eight corresponded to 1.9 per cent of the 420 patients treated with CPB before June, 1974. The pump priming fluid used was either Ringer's lactate solution alone or that containing a small amount of colloidal solution. Duration of CPB ranged from 52 min to 2 hrs and 42 min, but the FAC period was more than 3 hrs in each case. Acute renal failure occurred in 3 and 2 required peritoneal dialysis. Severe respiratory insufficiency occurred in 2 and one died 3 months after the operation. The most effective means to prevent the development of MNMS seems to be the local cooling of the cannulated limb during FAC. MNMS did not occur in 444 cases of CPB with FAC after July 1974, and here local cooling was applied in all cases.

Adolescent↗

[Clinical factors relating to the incidence of post-transfusion hepatitis following open heart surgery].

A retrospective study of post-transfusion hepatitis (PTH) has been made of 168 patients who had open-heart surgery between 1978 and 1981 at the Nagasaki University Hospital. The criteria of PTH was defined as an elevation of SGPT over 50 units with more than 2 weeks duration that occurred later than 3 weeks after the transfusion. PTH developed in 27 of the 168 patients (16%) and 26 of them were of the non-A, non-B type. The statistical analysis of these patients demonstrated that the following clinical factors significantly increased the incidence of PTH subsequent to open-heart surgery: (1) Use of plasma fractionating products made from pooled plasma, such as PPSB (p less than 0.001). (2) A large amount of blood and blood component transfusion (over 21 units, p less than 0.01). (3) Prolongation of the operation time (more than 330 minutes, p less than 0.05), cardiopulmonary bypass time (more than 90 minutes, p less than 0.05) and aortic cross-clamping time (more than 45 minutes, p less than 0.01), and (4) Surgery for cardiac lesions with left heart overloads (p less than 0.01).

Adult↗