The Gibbs' Boston years: early developments in epilepsy research and electroencephalography at Harvard. Interview by James L. Stone and John R. Hughes.
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Biomedical subjects
Publications and source records attributed to E L Gibbs.
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Psychomotor-variant is a rare clinico-electroencephalographic entity, characterized by a great variety of thalamic, hypothalamic and limbic symptoms and by a specific electrographic finding during light sleep, i.e. discharges of notch-topped 6 per second waves, chiefly in the temporal areas. It is rare, occurring among only one percent of patients with epilepsy or a question of epilepsy. Sixty-eight percent of patients with psychomotor-variant disorder improved symptomatically if treated with anti-epileptic medication.
A careful study of head injury in childhood shows that 14 and 6 per second positive spikes are not normal. They are a delayed reaction to mild injury and are more characteristic of slight injury than of severe injury, but they are common during recovery among patients with severe injury.
In routine electroencephalography, the likelihood of detecting existing abnormality, the quality of the interpretation, and the rate at which clinically correlated, standardized findings can be accumulated are greatly affected by the selection of electrode placements and the choice of montages. The Universal APEEGE System offers many practical advantages in comparison to the International 10-20 System. Extensive testing suggests that use of the Universal APEEGE System permits improved quality control and greater laboratory efficiency. It is hoped that the introduction of a new approach will stimulate healthy scientific competition and spur increasingly objective research and development in routine electroencephalography.
A convenient, low cost microfiche system for the random access, storage and retrieval of EEG data is described. Some of the more important advantages of microfilm in an EEG laboratory are: enormous data reductions; reduced operating costs; simplified records handling; improved communications between electroencephalographers; and access to an expanding number of inexpensive publications and reference materials.
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Dysgenesis of the eye produces occipital needle sharp spikes. Neither the age and maturational state of the eye nor the brain create the pathophysiologic conditions which give rise to needle sharp spikes. It seems rather that deafferentation of the visual cortex gives rise to an increase in its irritability which make it fire off in this special manner. Cannon and Rosenblueth presented evidence that, as a general rule, deafferented systems tend to become hyperexcitable.
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