PubMed Health⌕ Search

Biomedical subjects

E L Lindholm

Publications and source records attributed to E L Lindholm.

5 recordsLinked to original sources

Interobserver, interequipment and intersubject variability of echo-Doppler examination of the common carotid and vertebral arteries.

OBJECTIVE: We evaluated interobserver and interequipment variability in common carotid and vertebral flow measurements, using seven female members of nursing staff as subjects, four different ultrasound machines and three different radiologists as operators. METHODS: The flow of the common carotid and vertebral arteries in each subject was examined at 0, 10, 20 and 30 min after lying down in a supine position. Peak velocity, end-diastolic velocity, mean velocity, systolic acceleration, cross-sectional area of the vessel, flow volume/min, resistance index and Doppler angle were measured. RESULTS: A large proportion of the variance of peak velocity, cross-sectional area of the vessel and flow volume was patient-related. Significantly different values of end-diastolic velocity, mean velocity, resistance index, Doppler angle and systolic acceleration were obtained with different equipment. Significantly different values of systolic acceleration, vertebral peak velocity, common carotid artery flow and Doppler angle were obtained by different operators. However, part of the variability may be physiological due to the study protocol. CONCLUSION: The use of the same operator and equipment is recommended in follow-up examinations.

Analysis of Variance↗

Mammography and ultrasound in the diagnosis of contralateral breast cancer.

Forty-nine (5%) of 956 women referred for follow-up imaging after breast cancer treatment had a malignancy in both breasts. The mammograms and ultrasonograms or US reports, and histologic slides or pathologic reports of 31 of these patients were reviewed. Mammography was more sensitive than clinical examination or US in detecting contralateral breast cancer, the sensitivity of mammography being 81%. Thirty-nine percent of the contralateral cancers were nonpalpable, and all were first detected at mammography. No cancers were depicted by US alone. US provided complementary information about palpable masses in 50% of the cases in which the mammographic finding was difficult to interpret. The mammographic appearance and the difficulties in detecting a contralateral cancer were similar to those known to be characteristic for first primaries. Distinguishing a new primary from a metastasis from the first breast cancer was not always possible by means of mammography or US.

Adult↗

Breast cancer recurrence after mastectomy: diagnosis with mammography and US.

The authors reviewed mammograms and/or ultrasound (US) scans of 76 lesions (67 patients) suspected of being recurrent breast cancer. All patients had previously undergone mastectomy. Sixty-one cases were malignant disease and 15 were benign. Mammography and US were complementary to clinical examination in evaluating palpable lesions at the mastectomy site. Both imaging methods revealed nonpalpable recurrences. The sensitivity of US was 91%, whereas the sensitivities of clinical examination and mammography were 79% and 45%, respectively. US was the best imaging method for evaluating tumors in the chest wall far from the scar and in the axilla, as these could not be visualized on mammograms. Most recurrent cancers were seen as circumscribed masses at mammography and as hypoechoic lesions at US. Hyperechoic recurrences could not be differentiated from benign lesions. The value of early detection of recurrences with imaging methods remains to be seen.

Breast Neoplasms↗

Successful colposuspension in stress urinary incontinence reduces bladder neck mobility and increases pressure transmission to the urethra.

Twenty-nine consecutive patients with stress urinary incontinence were investigated by bead chain urethrocystography (UCG) and single cough urethrocystometry before operation and 8-12 months after a Burch colposuspension producing clinical improvement. The operation significantly elevated the bladder neck and reduced its mobility during acute stress. The urethral inclination angle and the posterior urethrovesical angle also became smaller at rest and on straining. A significant negative correlation was found between the postoperative mobility of the bladder neck and the post-operative pressure transmission ratio (PTR), indicating that correction of the urethrovesical anatomical disorder eliminates the functional disorder in this disease and restores continence.

Adult↗