Hypothalamic self-stimulation and duodenum motor activity.
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Biomedical subjects
Publications and source records attributed to E L Polyakov.
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Correlation between the frequency of bar pressing and the frequency of hypothalamic self-stimulation of fixed duration was studied in cats during changes in strength of the stimulating current. Strong direct correlation was found between the frequency of bar pressing and the frequency of self-stimulation, whereas strong negative correlation was found between the frequency of pressing and the animal's "work effectiveness." It is suggested that the strongest motivation arises in the presence of an optimal strength of self-stimulation, giving rise to maximal frequency of bar pressing.
We measured changes in the frequency of hypothalamic self-stimulation in cats during their stays in a normal-oxygen nitrogen-oxygen environment under a pressure of 6 kg/cm2. A 200-300% increase in the frequency of self-stimulation was observed during the initial exposure. A depression of the reaction with a subsequent normalization by the third day took place after decompression. The second exposure led to an adaptation of the organisms to the effect of the elevated partial pressure of nitrogen. It is suggested that the changes in the self-stimulation reaction are connected with the "narcotic" effect of nitrogen under elevated pressures.