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Biomedical subjects

E Lais

Publications and source records attributed to E Lais.

17 recordsLinked to original sources

[Gadolinium-DTPA enhanced MRT in the evaluation of the healing of autologous patellar ligament transplants for anterior cruciate ligament reconstruction].

Eighteen patients with autologous patellar tendon transplant for reconstruction of the anterior cruciate ligament were examined postoperatively. The time between operation and MR study was up to 3 weeks in ten patients, between 3 and 35 weeks in three patients and more than 35 weeks in five patients. In all patients, Gd-DTPA enhancement on the surface of the ligamentous transplant was visualized. This enhancement was between 1 and 10 mm thick. In all patients, complete stability of the knee joint was achieved, postoperatively. In 15 patients flexion and extension were normal at the postoperative investigation. Three patients had a limitation of knee movement. In these MR studies, significant hyperplasia of the synovial membrane of the entire joint was diagnosed, explaining the persisting problems. Gd-DTPA-enhanced MR of the knee joint allows non-invasive documentation of remodelling following a patellar ligament transplant and possible complications.

Adolescent↗

[Volar plate osteosynthesis in typical and atypical distal radius fractures].

28 patients with a fracture of the distal end of the radius were treated by a T-plate osteosynthesis through the volar approach. There were 7 unstable distal metaphyseal fractures and 21 dislocated intra-articular fractures. 21 patients were investigated 6 months to 8 years after operation according to the scheme of Sarmiento. 17 patients had a good or excellent result, 4 patients a fair or poor result. 2 patients developed a Sudeck's dystrophy (Algodystrophy), one of them with a radial-ulnar bone bridge. The volar application of the plate is indicated for flexion and extension fractures. In cases with compression of the dorsal cortex a bone graft is indicated to improve a stable osteosynthesis. A conventional tomography on two views helps to diagnose exactly an intra-articular fracture and to decide whether to use a plate or pins and external fixation after open reduction. Remanipulation or an operation 2 weeks after trauma increases the risk of a Sudeck's dystrophy and leads to a poor result.

Adult↗

[Perforation of a duodenal stress ulcer in a 7-year-old polytraumatized boy].

This is a report of a seven-year-old polytraumatised boy with perforation of a duodenal stress-ulcer. Aspects of the etiology and pathogenesis were discussed. The main therapeutical efforts by stress-ulcer risk patients consist in an early sufficient shock therapy and adequate stress-ulcer prophylaxis to prevent the origin of stress-ulcers and their complications like bleeding and perforation.

Child↗

[Fracture and dislocation fracture of the os pisiforme].

Four cases of pisiform fracture are presented. In one case the largest fragment of the pisiform bone with the articular surface was dislocated. After open reduction, osteosynthesis with K-wires was performed. Two patients had an isolated fracture without fragment dislocation. They had their lower arms immobilized with a plaster of Paris cast for 4 weeks. In the fourth case the fracture of the pisiform bone was associated with an intraarticular distal radial fracture and wrist dislocation. The typical traumatic cause of pisiform fracture is a fall onto the outstretched hand. Immobilization for 4 weeks results in functional recovery. In cases with dislocation of the pisotriquetral joint open reduction and osteosynthesis are necessary. Excision of the pisiform bone is not indicated in a fresh injury.

Adult↗

[A NMR tomographic follow-up assessment of the replacement plastic repair of the anterior cruciate ligament with an autologous ligamentum patellae transplant].

Reconstruction of the anterior crucial ligament can be performed by using an autogenous transplant from the patellar ligament. Employing postoperative MR investigation, reaction of the non-vascularised tendon was studied. In 16 patients 20 knees were investigated by applying a 1.5 tesla magnet with T1-weighted (TR 500 ms, TE 15 ms) and a T2*-weighted (FISP 3D: TR 30 ms, TE 10 ms, flip angle 40 degrees). Postoperative MR follow-up showed an increase in signal intensity and diameter in T1-weighted images. This represents revascularisation of the transplant.

Anterior Cruciate Ligament↗

[Reconstruction of the proximal insertion of the anterior cruciate ligament. Studies on the accuracy of a non-instrumental method].

The isometry of the femoral and tibial insertion is of decisive importance for the stability of a prosthetic anterior cruciate ligament. A large number of techniques and instruments have been developed to determine the point of isometric femoral insertion. Experiments with 20 cadaveric knees show that the proximal insertion of the anterior cruciate ligament is accurately reconstructed by means of the surgical procedure briefly presented in this paper; the use of positioners is not necessary.

Anterior Cruciate Ligament↗

[2-dimensional CT arthrotomography in the postoperative follow-up of a new anterior cruciate ligament plasty].

Fifty-eight patients underwent intraarticular reconstruction of the anterior cruciate ligament. This was performed by using an autogenous transplant from the mid portion of the patellar ligament with a proximal and distal bone block, as described by Hertel. For comparison with the conventional X-ray examination, HRCT was performed to study the early postoperative results. In four patients (7%) dislocation of the bone block in the femoral condyle was seen. Two-dimensional reconstruction proved to be a satisfactory method for demonstration of the exact position of the autogenous transplant in both coronary and sagittal planes.

Adolescent↗

[Optimal treatment of complex ligament injuries and biomechanical aspects].

Certain guidelines may be established for surgical treatment of complex lesions of genicular ligaments. Preferential treatment should be given to the central stabilizers, anterior and posterior cruciate ligaments. Suturing with autologous augmentation is the rule for the anterior cruciate ligament, whereas the posterior cruciate ligament should be stabilised by both suturing and relief, using a transosseous PDS cord. The main peripheral ligaments, internal and external ligaments as well as arcuatum complex, have to be sutured, once instability has been confirmed. In cases of complex injuries, lateral structures are more important than median peripheral structures. Sutures should be tied for good stability. Non-absorbable material is used in cases in which stability of anchorage should enable no-plaster after-care. Sutured ligaments should be tension-adjusted close to stretching position (Lachman position, for main ligaments) and with neutral rotation. Sutures in shortened position may undergo rupture and thus jeopardize suturing at all. Only sutures for the posterior cruciate ligament should be strained close to rectangular position, since this actually represents maximum tension of the posterior cruciate ligament. Knee joint luxation is usually based on damage to all three ligaments, though two-ligament injuries are possible. Surgery is the optimum approach, since it is the only way to accomplish mechanically favourable adaptation of the central stabilizers.

Biomechanical Phenomena↗

[Perioperative antibiotic therapy--clinical experiences with a combination of mezlocillin/sisomicin in accident surgery].

The clinical and bacteriological efficiency of the combination Mezlocillin and Sisomicin was studied in 25 patients from the Department of trauma. In 9 cases the combination of antibiotics was used for treatment of manifest infections. 16 patients received a prophylaxis before and after operation. Among them were patients with open fractures, with a large soft tissue damage, polytraumatized patients with multiple injuries or patients with pathological fractures. Dosage of Mezlocillin was 4 g every 8 h, and dosage of Sisomicin was 75 mg every 8 h. Mean duration of therapy was 6 days. In 24 cases the combination of antibiotics was successful. In one case occurred a postoperative haematoma without bacterial findings. In all infections (9 cases) isolated germs were achieved with the combination Mezlocillin and Sisomicin.

Drug Therapy, Combination↗

[Lack of effect of oral zinc sulfate on wound healing in leg ulcer].

The effect of oral zinc on the healing of chronic venous leg ulcers has been investigated in 91 hospitalized patients aged approximately 70 years. The patients were divided into three groups: group A consisted of patients with serum zinc concentrations in the upper normal range (Zn greater than or equal to 1.0 mg/l) who received no zinc therapy. Groups B and C consisted of patients with serum zinc concentrations in the lower normal range (Zn less than 1.0 mg/l) who received either 3 daily doses of 220 mg zinc sulphate (group B) or placebo (group C). In group B, a marked increase in serum zinc concentration occured within one month (from 0.9 to 1.25 mg/L). In group A, serum zinc levels decreased slightly during the observation period of three months (from 1.1 to 1.0 mg/l) while a slight rise was seen in group C (from 0.9 to 1.0 mg/l). The healing rate of the ulcers in group A was not superior to that in group C. Zinc substitution in the low zinc group B did not improve healing as compared to placebo-treated low zinc group C. A favourable effect of oral zinc on wound healing in patients with initially low serum zinc concentrations could not be demonstrated. Initial ulcer areas were significantly smaller in patients with higher serum zinc levels than in patients with lower serum zinc levels. Low serum zinc levels appear to be a consequence of insufficient nutrition, an observation which may indicate a correlation between nutritional deficiency and ulcer area. The healing rate did not depend significantly upon age, sex, weight or cause. It was, however, accelerated in the case of larger ulcers.

Administration, Oral↗