PubMed Health⌕ Search

Biomedical subjects

E Lakomy

Publications and source records attributed to E Lakomy.

3 recordsLinked to original sources

[Effectiveness of antiviral treatment of patients with chronic hepatitis C (a Polish multicenter study)].

Interferon alpha (INF) is routine treatment in patients with chronic hepatitis C. Many controlled investigations were evaluated to establish the optimal schedule of treatment with sustained virological and biochemical response. Recently, multicentre meta-analyses suggest that combination therapy (INF + Ribavirin) was more effective than treatment with interferon alone. The aim of this study was to compare the efficacy of four schedules of antiviral treatment in 445 patients with chronic hepatitis C. Combination therapy (INF + Ribavirin) given for 6 mo. and monotherapy (INF) for 18 mo. were more effective than interferon alone given for 6 mo. Treatment with INF alone for 6 mo. was demonstrated to be insufficient.

Antiviral Agents↗

[Borreliosis--Lyme disease--a growing clinical problem].

Clinical and epidemiological analysis of Lyme disease cases treated at the Infectious Diseases Clinic of the Medical University of Gdańsk and the District Hospital of Infectious Diseases in the years 1993-1995 was done. The results were compared to data presented in the literature. The material consisted of 184 patients, 169 in I stage of the disease and 15 in the II stage. Out of 15 in the II stage, 2 patients presented with lymphocytoma benigna cutis, 7 with arthritis and 6 with neuroboreliosis. The Lyme disease diagnosis was confirmed with positive serological tests in 45% of patients in the I stage and in 100% of patients in the II stage. Over the analysed time interval, 1993-1995, the incidence of Lyme disease has increased markedly; 1993-38 cases, 1994-50 cases and 96 cases in 1995.

Adolescent↗